Morteza Alijanpour Aghamaleki
Pediatric endocrinologist, Non-communicable Pediatric Disease Research Center, Babol University of Medical Sciences, Babol, IR Iran.Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran
[ 1 ] - Incidence, predisposing factors and complications of Diabetic Ketoacidosis in diabetic patients
Background: Diabetic ketoacidosis (DKA) is the final consequence and life-threatening complication of severe insulin deficiency in type 1 diabetes with occurrence of 20-40%. The aim of this study was to investigate the incidence and predisposing factors of DKA and its consequences. Methods: This retrospective study was performed on 128 diabetic patients in Amirkola Children’s Hospital ...
[ 2 ] - Effect of Vitamin D Supplementation on Pancreatic Β -Cell Function in Patients with Type 1 Diabetes Mellitus and Vitamin D Deficiency: A Clinical Trial Study
Background Considering the increasing prevalence of type 1 diabetes mellitus (T1DM) as an autoimmune disease in recent years and the positive effects of vitamin D (VD) on this disease, especially the preventive effect of VD on progressive reduction of pancreatic β-cells, we aimed to investigate the effect of VD on pancreatic β-cell function in T1DM patients. Materials and Methods From Sep 2016 ...
[ 3 ] - ژن های عامل بیماری ادرار شربت افرا ، پاتو مکانیسم مولکولی بیماری و جهش های جمعیت ایران
سابقه و هدف: بیماری ادرار شربت افرا (MSUD) یک اختلال متابولیک مادرزادی است که به علت نقص در کمپلکس آلفاکتواسید دهیدروژناز شاخهدار به وجود آمده و موجب تجمع اسیدآمینههای شاخهدار در مایعات بدن میشود.این کمپلکس توسط ۴ ژن هستهای BCKDHA، BCKDHB، DBT، DLD کد شده و اختلال در هر یک از این ژنها باعث بروز این بیماری میشود. تجمع متابولیتها منجر به اختلال در متابولیسم انرژی، تحریک آپوپتوز، اختلال در ...
[ 4 ] - Effect of levothyroxine on cardiac function in children with subclinical hypothyroidism: A quasi-experimental study
Background: Because of the importance of thyroid function and its effect on different organs, such as the heart, this study was aimed to evaluate the effect of levothyroxine on cardiac function in children with subclinical hypothyroidism. Methods: This quasi-experimental study was performed on children aged 4-12 years old with diagnosis of subclinical hypothyroidism in Amirkola Children's Hosp...
[ 5 ] - The incidence of hyperglycemia during the induction phase of chemotherapy in patients with acute lymphoblastic leukemia
Background: Hyperglycemia is one of the most complications of corticosteroid and asparaginase during induction phase of chemotherapy in children suffering from acute lymphoblastic leukemia (ALL). This study was carried out to evaluate the incidence of hyperglycemia and associated risk factors during chemotherapy induction phase at Amirkola Children's Hospital. Materials and Methods: In this c...
[ 6 ] - Effect of Vitamin D Therapy on Hashimoto's Thyroiditis in Children with Hypovitaminosis D
Background Hashimoto's thyroiditis (HT) is a common cause of thyroid diseases in children and the role of vitamin D (VD) is controversial. Therefore, the aim of this study was to investigate the influence of VD therapy on HT in children with hypovitaminosis D.<br...
[ 7 ] - Therapeutic Effects of Recombinant Growth Hormone in Improving the Growth of Thalassemia Major Patients: A Retrospective Study
Background and purpose: Beta thalassemia major is one of the most common inherited blood diseases and patients with this condition require regular blood transfusions. The resulting iron overload deposition causes endocrine gland disorders, including growth hormone (GH) abnormality. In this study, we examined the effects of recombinant growth hormone (rGH) in these patients. Materials and metho...
[ 8 ] - Correlation between HbA1c Levels and Depression in Children and Adolescents with Type 1 Diabetes
Background and purpose: Type 1 diabetes mellitus (T1DM) is a chronic disease with multiple long-term complications that could trigger depression. This study was performed to determine the relationship between HbA1C levels and depression in children and adolescents with T1DM. Materials and methods: This cross-sectional study was conducted in all children and adolescents with T1DM attending an e...
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