Ali Akbar Samadani
Cellular and Molecular Biology Research Center, Babol University of Medical Sciences, Babol, Iran.
[ 1 ] - RNA Extraction from Animal and Human\'s Cancerous Tissues: Does Tissue Matter?
The reliability of gene expression profiling based technologies and methods to find transcriptional differences representative for the original samples is influenced by the quality of the extracted RNA. Hence, RNA extraction is the first step to investigate the gene expression and its function. Consequently, the quality of extracted RNA is really significant. Correspondingly, this research was ...
[ 2 ] - Histopathological investigation of Skin Cancer and Study of CDKN2A Gene Polymorphism in Mazandaran Province, Iran
Skin cancer is one of the most important type of cancers in the world. In this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. In this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of CDKN2A gene. This case-control study w...
[ 3 ] - Bone Mineral Density and Cystic Fibrosis: A Review
Cystic fibrosis (CF) is a common progressive genetic disorder among children which involves lungs, kidneys, intestine and liver. Apart from the significance of genetic factors, various environmental factors particularly bone mineral density are directly associated with CF. Remarkably, bone disease is appeared as a routine and commo...
[ 4 ] - Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma
Gastric cancer (GC) is considered as one of the most serious cancers, and in Iran, due to environmental factors in different regions, it has a high frequency. Apart from environmental factors, genetic and epigenetic ones also play a key role in the development of carcinogenesis of GC. In this regard, the study of functioning of the molecular mechanisms involved in the carcinogenesis and also tu...
[ 5 ] - Henoch-Schonlein purpura (HSP) in a rare novel complicated case: A case report
Introduction: Hcnoch-Schonlein purpura is an IgA mediated small-vessel vasculitis and it is so common in children. The classic term of signs and symbols include polpuble purpura, arthralgia/arthritis, abdominal pain and also renal disease. The incidence of HSP in older age of the entire gastrointestinal tract (gastric, small intestine and large intestine) without arthritis/arthralgia and kidn...
[ 6 ] - Correlation between the degree and stage of malignancy with environmental factors based on gender and age of patients in colorectal cancer patients
Introduction: Colorectal cancer is the third most common cancer in Iran. Some studies have shown that age and sex are associated with the course and prognosis of colorectal cancer. Due to the fact that recognizing the factors affecting colorectal cancer improves the screening system and selects better treatment modalities, and due to the lack of such studies in Iran, in this study, the relation...
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