Mahdih Faghihi

[ 1 ] - Preconditioning effects of oxytocin in reducing cardiac arrhythmias in a rat heart regional ischemia-reperfusion model

Abstract Introduction: Occurrence of cardiac arrhythmias and myocardial infarction are two main deleterious events that are caused by ischemia-reperfusion (IR) injury in the heart. Cardiac preconditioning represents the most potent method of rescuing heart tissue from undergoing irreversible ischemic damage. The aim of the present study was to evaluate oxytocin (OT) cardioprotective effect...

[ 2 ] - Effect of pre-treatment with oxytocin on cardiac enzymes in regional ischemiareperfusion injury induced in the rat heart

Introduction: Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. The aim of the present study was to evaluate oxytocin (OT) induced cardioprotection and its signaling pathways on lactate dehydrogenase (LDH) and creatine kinase-MB isoenzyme (CK-MB) in the anesthetized rats. Methods: Ei...

[ 3 ] - Regular Exercise or Food Restriction, Which is Better in the Event of Heart Failure? An Approach to Oxidative Stress and Angiogenesis

The aim of present study was to investigate whether food restriction combined with exercise training could attenuate the oxidative stress and promote angiogenesis in a rat model of heart failure. 50 male wistar rats weighing 250-300 g were randomly divided into 5 groups including: 1) sham; they were fed ad libitum food, n=10. 2) Heart failure group; 3) Exercise group; they run on a treadmill 5 ...

[ 4 ] - Cardioprotective effect of ethanolic leaf extract of Melissa officinalis L against regional ischemia-induced arrhythmia and heart injury after five days of reperfusion in rats

Abstract Melissa officinalis has antioxidant and anti-inflammatory activities and is used in various diseases. Aim of the study: We investigated the role of M. officinalis extract (MOE) against ischemia-induced arrhythmias and heart injury after five days of reperfusion in an in-vivo rat model of regional heart ischemia. The leaf extract of M. officinalis was standardized thr...

[ 5 ] - Cardioprotective effect of ethanolic leaf extract of Melissa officinalis L against regional ischemia-induced arrhythmia and heart injury after five days of reperfusion in rats

Abstract Melissa officinalis has antioxidant and anti-inflammatory activities and is used in various diseases. Aim of the study: We investigated the role of M. officinalis extract (MOE) against ischemia-induced arrhythmias and heart injury after five days of reperfusion in an in-vivo rat model of regional heart ischemia. The leaf extract of M. officinalis was standardized thr...