Farshid Yeganeh
Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
[ 1 ] - Vitrification Affects Nuclear Maturation and Gene Expression of Immature Human Oocytes
Background: Vitrification of oocytes is a fast-freezing technique, which may affect the quality of the human oocyte, and consequently affects the embryo development, pregnancy and birth. The aim of the current study was to investigate the consequence of in-vitro vitrification on maturation status of immature human oocytes, additionally, expression levels of stress, and apoptosis related genes. ...
[ 2 ] - The Impact of Ramadan Fasting on SIRT1 mRNA Expression in Peripheral Blood Mononuclear Cells
Background:The aim of this study was to evaluate the effect of Ramadan fasting on SIRT1 mRNA expression in healthy men.Islamic Ramadan fasting is a holy religious ceremony that has many spiritual benefits. Additionally, it can be considered as the equivalent of calorie restriction that may affect physical health. The results of previous studies revealed that calorie restriction increases the li...
[ 3 ] - Roles of Chromatin insulators in gene regulation and diseases
With advances in genetic science, the dynamic structure of eukaryotic genome is considered as basis of gene expression regulation. Long-distance communication between regulatory elements and target promoters is critical and the mechanisms responsible for this connection are just starting to emerge. Chromatin insulators are key determinants of proper gene regulation and precise organization of c...
[ 4 ] - بررسی سطح سرمی مولکول(DPPIV/CD26) در بیماران مبتلا به درگیری کلیوی لوپوس
Abstract Background: Lupus is one of the most common autoimmune diseases. IFN-α as an important factor in the pathogenesis of lupus has been introduced. Also, CD26 with its enzymatic activity has many roles in the regulation of immune responses. In the current study, we investigated the level of CD26 and IFN-α in the serum of SLE patients. Materials and methods: In this case-control study, 46 S...
[ 5 ] - Study of the immune adjuvant effect of chitin microparticles on plasma levels of IgG1 and IgG2a during immunization against Leishmania infection in BALB/c mice
Background: There are reports on the ability of chitin microparticles to modulate the TH1 and TH2 responses, depending on the size and administration route. The purpose of the present study was to investigate the immunoadjuvant effects of the small-sized (less than 40 microns) chitin microparticles (CMP) in vaccination against Leishmania major for preventing leishmaniasis in BALB /c mice by ...
[ 6 ] - Activity of Dipeptidyl Peptidase-IV/CD26 and Aminopeptidase N/CD13 in Secretome of Mesenchymal Stem Cells after Treatment with LPS and PMA
Background: Emerging evidence suggests that secretome of mesenchymal stem cells has many anti-inflammatory and regenerative properties, which makes it a suitable candidate for the treatment of autoimmune and degenerative diseases. Dipeptidyl Peptidase-IV (DPP-IV)/CD26 and Aminopeptidase N (APN)/CD13 are ubiquitous ecto-enzymes which can digest various substrates including some ...