Mojtaba Ziaee

Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

[ 1 ] - Sleep deprivation disrupts striatal anti-apoptotic responses in 6-hydroxy dopamine-lesioned parkinsonian rats

Objective(s): The present study was conducted to examine the effect of sleep deprivation (SD) on the anti-apoptotic pathways in Parkinsonian rats. Materials and Methods: Male Wistar rats (n = 40) were assigned to four groups (10 animals each): sham surgery (Sham), 6-hydroxydopamine (6-OHDA)-lesioned (OH), 6-OHDA-lesioned plus grid control (OH+GC), 6-OHDA-lesioned plus SD (OH+SD). Parkinson’s di...

[ 2 ] - Clinical efficacy of Silybum marianum seed extract in treatment of type 2 diabetes mellitus and non-alcoholic fatty liver disease: a narrative review

Background: Several clinical studies have been undertaken to investigate the potential therapeutic effects of Silybum marianum (S. marianum) seed extract (silymarin) in Type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). Objective: We performed the present narrative review to evaluate the efficacy of silymarin supplement for treatment of T2DM and NAFLD. Methods: Elect...