Hasan Rezaei-Seresht

Traditional and Complementary Medicine Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran

[ 1 ] - Cytotoxic activity of caffeic acid and gallic acid against MCF-7 human breast cancer cells: An in silico and in vitro study

Objective: Phenolic compounds have been considered inhibitors of various cancers. Material and Methods: In this study, caffeic acid and gallic acid were appraised for their possible effects on apoptotic genes expression in a breast cancer cell line in vitro. We also evaluated ligand interaction and ligand binding with estrogen receptor alpha by m...

[ 2 ] - Antioxidant activity and Cytotoxicity Effect of Various Extracts of Sclerorhachis platyrachis on the Human breast adenocarcinoma Cells

Background and Aim: One of the spices of compositae is the Sclerorhachis platyrachis that is Iranian native. This aromatic plant has been known as bacterial growth inhibitor. This study have been attempted to investigate antioxidant activity and cytotoxicity effect of Sclerorhachis platyrachis extractson the MCF-7 cell line. Materials and Methods: The Hexane (HE), Chloroform (CE), Ethyl acetate...

[ 3 ] - Chenopodium Botrys as a Source of Sesquiterpenes to Induce Apoptosis and G1 Cell Cycle Arrest in Cervical Cancer Cells

Conducting cell apoptosis pathways is a novel strategy in cancer treatment. This study aimed to explain that C. botrys essential oil could induce apoptosis and arrest the cell cycle in HeLa cells. Cytotoxic and apoptogenic effects of the essential oil of Jerusalem-oak (Chenopodium botrys L.), which was obtained from the aerial parts of the plant, were evaluated in HeLa cells. Cell viability was...

[ 4 ] - Chenopodium Botrys as a Source of Sesquiterpenes to Induce Apoptosis and G1 Cell Cycle Arrest in Cervical Cancer Cells

Conducting cell apoptosis pathways is a novel strategy in cancer treatment. This study aimed to explain that C. botrys essential oil could induce apoptosis and arrest the cell cycle in HeLa cells. Cytotoxic and apoptogenic effects of the essential oil of Jerusalem-oak (Chenopodium botrys L.), which was obtained from the aerial parts of the plant, were evaluated in HeLa cells. Cell viability was...