Rezvan Najafi

Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

[ 1 ] - Cross-Resistance of Acquired Radioresistant Colorectal Cancer Cell Line to gefitinib and regorafenib

Background: Usually, chemoradiotherapy can be used for the treatment of locally advanced colorectal cancer (CRC) before surgery. On the other hand, some studies have shown that fractional radiation of tumor cells leads to chemoresistance. The aim of this study was to evaluate the chemoresistance of radioresistant sub-line (RR sub-line).Methods: This study was done in Hamadan University of...

[ 2 ] - Effects of treadmill exercise and preconditioned bone marrow- derived mesenchymal stem cells transplantation on Aβ-induced neurotoxicity in male rats

Introduction: Preconditioning of mesenchymal stem cells (MSCs) is a promising strategy to enhance the therapeutic properties of transplanted MSCs. In this study, we investigated the synergistic effects of treadmill exercise and dimethyloxalylglycine (DMOG)-preconditioned stem cells in an Alzheimer’s disease (AD) model. Materials and Methods: DMOG- treated MSCs were intravenously transplanted in...