Saeid Afshar
Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
[ 1 ] - Cross-Resistance of Acquired Radioresistant Colorectal Cancer Cell Line to gefitinib and regorafenib
Background: Usually, chemoradiotherapy can be used for the treatment of locally advanced colorectal cancer (CRC) before surgery. On the other hand, some studies have shown that fractional radiation of tumor cells leads to chemoresistance. The aim of this study was to evaluate the chemoresistance of radioresistant sub-line (RR sub-line).Methods: This study was done in Hamadan University of...
[ 2 ] - Effects of Melatonin on IL-6 Serum Level Changes and Fatigue Caused by Adjuvant Chemoradiotherapy in Breast Cancer Women: A Randomized Controlled Trial
Introduction: Cancer-related fatigue is one of the most common and debilitating complications of breast cancer. Cancer patients have been found to have lower levels of melatonin, and fatigue has been shown to be correlated with both melatonin and interleukin (IL-6) in cancer patients. This study aimed to evaluate the fatigue and serum level of IL-6 in response to melatonin treatment in breast c...
[ 3 ] - Significance of exosomes in COVID-19 pathogenesis and therapy
Exosomes are lipid bilayer-enclosed nano-sized vesicles, which carry various biomolecules including proteins, lipids, and microRNAs. SARS-CoV-2-loaded exosomes can be entered into the susceptible host cells, and transported viral components which are associated with viral particles intercellular transmission and spread of infection. Over-stimulation of the immune system followed by excessive pr...
[ 4 ] - Evaluation of miR-330-3p and BMI1 Expression in Colorectal Cancer Patients, Healthy Adjacent Tissues, and Polypoid Adenomatous Lesions
MicroRNAs (miRNAs) have emerged as essential gene expression regulators associated with human diseases such as colorectal cancer (CRC). The purpose of this study was to evaluate the expression of miR-330-3p and its target gene BMI1 in tissue samples of patients with CRC, polyp, and healthy adjacent tissue samples and their association with clinicopathological and demographic factors such as age...
نویسندگان همکار