Ghorbanmovahed, Mahtab
Department of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran
[ 1 ] - Inhibitory and Stimulatory Effects of Some Metals on Asparaginase Activity Produced by Staphylococcus MGM1
Background: Asparaginases are known to be the cornerstone for the treatment of acute lymphoblastic leukemia (ALL) and are used for treatment in all pediatric regimens as well as in the majority of adult treatment protocols. Clinical hypersensitivity reactions against commercially available asparaginase have resulted in the failure in the treatment of ALL in more than 60% of cases. Thus, it is...
[ 2 ] - An Overview of Asparaginase Enzyme Features: An Anticancer Enzyme with High Potency
Introduction: One of the important findings in the pharmaceutical and medical industry is the use of the asparaginazase enzyme as an anticancer drug. The asparaginase enzyme, hydrolyzing the amino acid of asparagine, reduces this amino acid in the blood and causes the death of cancer cells. Today, the enzyme is used to treat various types of leukemia, particularly acute lymphoblastic leukemia, ...
[ 3 ] - A Review of The Role of The Microbiome on Immune Responses and Its Association With Cystic Fibrosis
In recent years, the microbiome has been recognized as a key regulator of immune responses. Evidence suggests that changes in the microbiome can lead to chronic disease and even exacerbation of the disease. Impairment of innate immunity resulting from microbial incompatibility may worsen host susceptibility to infection and exacerbate chronic lung diseases. Specific microbes play a key role in ...
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