سید مسعود نبوی

دکترای تخصصی، گروه پزشکی، دانشگاه علوم پزشکی شاهد، تهران، ایران

[ 1 ] - مقایسه دید رنگ بیماران مبتلا به مالتیپل اسکلروزیس

هدف:  مطالعه حاضر با هدف ارزیابی کمی دید رنگ بیماران مبتلا به مالتیپل اسکلروزیس  Multiple Sclerosis(MS)نوع عود و فروکش با و بدون علائم بینایی با استفاده از تست D15 انجام گرفت. روش بررسی: در این مطالعه 100 چشم از 50 بیمار مبتلا به MS (30 بیمار دارای علائم بینایی و 20 بیمار بدون علائم بینایی) و 50 چشم از 25 فرد نرمال  به عنوان گروه مقایسه با محدوده سنی 40- 18سال مورد ارزیابی قرار گرفت. در تقسیم‌ ...

[ 2 ] - بررسی اختلالات قاعدگی و عوامل مرتبط با آن در زنان مبتلا به مولتیپل اسکلروزیس

مقدمه: مولتیپل اسکلروزیس، شایع‌ترین بیماری خود­ایمنی است که اغلب زنان سنین باروری را تحت تأثیر قرار می‌دهد. یکی از شکایات بالینی در زنان مبتلا، ابتلاء به انواعی از اختلالات قاعدگی است. مطالعه حاضر با هدف بررسی اختلالات قاعدگی و عوامل مرتبط با آن در زنان مبتلا به مولتیپل اسکلروزیس انجام شد. روش‌کار: این مطالعه توصیفی- مقطعی در سال 96-1395 بر روی 172 زن مبتلا به MS مراجعه‌کننده به کلینیک خصوصی م...

[ 3 ] - Can hand dexterity predict the disability status of patients with multiple sclerosis?

  Background: Multiple Sclerosis (MS) is the most common disabling neurological disease. Hand dysfunction is one of the main complaints of patients with MS. The present study aimed to compare hand dexterity of MS patients with low Expanded Disability Status Scale (EDSS) scores and healthy adults. It also sought to identify the predictors of disability status of patients with MS based on their m...

[ 4 ] - The effect of exercise therapy on cognitive functions in multiple sclerosis patients: A pilot study

  Background: The positive impacts of exercise therapy on patients’ cognitive problems still remain unknown. This study was a pilot intervention to examine the effects of combined exercise on the cognitive problems of patients with multiple sclerosis (MS) in Iranian MS Society over 2012 to 2013.   Methods : This quasi-experimental research was carried out in the form of a pretest/posttest study...

[ 5 ] - Psychometric Properties of the Persian Version of the Fatigue Impact Scale (FIS-P) in Patients with Multiple Sclerosis

Objectives: This study was designed to evaluate the psychometric features of the Persian version of the Fatigue Impact Scale (FIS-P) tool when used in Iranian MS patients. Methods: 140 MS patients and the equivalent number of healthy controls completed the following assessments: FIS-P, Fatigue Severity Scale (FSS), SF-36 questionnaire and  the Mini-Mental State Examination (MMSE). ...

[ 6 ] - In Silico Perspectives on the Prediction of the PLP’s Epitopes involved in Multiple Sclerosis

Background: Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system (CNS). The main cause of the MS is yet to be revealed, but the most probable theory is based on the molecular mimicry that concludes some infections in the activation of T cells against brain auto-antigens that initiate the disease cascade.Objectives: The Purpose of this research is the...

[ 7 ] - A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran

We compared the efficacy and safety of a biosimilar form of beta-interferon-1a (Actovex) versus the reference product in the treatment of relapsing remitting multiple sclerosis (RRMS). In a double blind, randomized phase 3 clinical trial, we evaluated 138 patients with RRMS that were allocated to receive the biosimilar medication and the reference treatment (30 μg intramuscular, weekly for one ...

[ 8 ] - A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran

We compared the efficacy and safety of a biosimilar form of beta-interferon-1a (Actovex) versus the reference product in the treatment of relapsing remitting multiple sclerosis (RRMS). In a double blind, randomized phase 3 clinical trial, we evaluated 138 patients with RRMS that were allocated to receive the biosimilar medication and the reference treatment (30 μg intramuscular, weekly for one ...

[ 9 ] - Effect of Expressive Writing on Promotion of Body Image in Women with Multiple Sclerosis: A Randomized Controlled Trial

 Background and purpose: Multiple sclerosis (MS) affects own physical function and body image. The aim of this study was to determine the effect of expressive writing on body image in women with MS. Materials and methods: In this randomized trial, the Solomon four-group design was employed. The study was carried out in 116 women attending an MS clinic in Tehran, Iran 2019. The participants wer...

[ 10 ] - Evaluation the effect of the health promotinglifestyle by multimedia education on sexual function in women with multiple sclerosis

Background and Aim: Multiple sclerosis is the most common progressive neurological disease in young people and affects women several times more than men. Sexual problems are one of the most common symptoms in affected women, which have a great impact on the couple’s relationship and are often ignored. Therefore, the present study aimed to determine the effect of health-promoting multimedia educ...

[ 11 ] - After introduction of advanced therapeutic medicinal products (ATMPs) in Ischemic Stroke; novel therapeutic modalities from financial perspective

Stroke, is accounting for more than 34% of total healthcare spending globally. Ischemic stroke (IS) accounts for 62.4% of incident stroke cases. IS-related direct medical expenditures place a considerable burden on healthcare system. The burden is more prominent in developing countries where limitations in insurance coverage is a big concern. It would be less challenging in developed countries,...