مرضیه یگانه فر

کارشناسی ارشد کتابداری, کتابدار کتابخانه عمومی

[ 1 ] - بررسی جایگاه موجود و مورد انتظار بخش کودکان و نوجوانان در کتابخانه های خراسان رضوی

هدف: هدف این پژوهش، بررسی وضعیت خدمات کودکان و نوجوانان درکتابخانه‎های ‎عمومی خراسان رضوی و مقایسة آن با 7 معیار استخراج شده از متون، به منظور ارزیابی این نوع خدمات است. روش پژوهش: پژوهش حاضر در چهار مرحله و با استفاده از رویکرد کمّی و کیفی انجام شد.جامعة هدف شامل 3 گروه کتابخانه‌های کانون پرورش فکری کودکان و نوجوانان، کتابخانه‌های عمومی دارای بخش کودک و ن...

[ 2 ] - Assessment of in vitro radiosensitivity parameters of breast cancer cells following exposure to radiotherapy hospital-based facilities

Introduction: The aim of the present study was to assess the radiosensitivity parameters for SK-BR-3 (SKBR3) breast cancer cells that could be implemented in the cutting-edge treatment planning systems (TPS) for accelerated partial-breast irradiation (APBI). Materials and Methods: The cell survival fraction and its relevant radiosensitivity coefficients, namely α and β, in linear-quadratic (LQ)...

[ 3 ] - طراحی و راه اندازی روش TaqMan Real-time PCR جهت تشخیص و تعیین کمی ویروس نقص ایمنی اکتسابی نوع1 (HIV-1)

Background: Human Immunodeficiency Virus Type 1 (HIV-1) is one of the most important blood-borne infectious viruses that are considered a global problem, thus it is important to diagnose it with high accuracy and sensitivity. Serologic methods do not adequately detect this infection. Therefore, the purpose of the present study was to design a sensitive method based on TaqMan Real-time PCR me...

[ 4 ] - Effect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells

Objective(s): MicroRNAs (miRNAs) could regulate many cellular processes such as proliferation and differentiation. let-7a miRNA is one of the key regulators in the developmental transition of retinal progenitor cells into differentiated cells. Current evidence suggests that mesenchymal stem cells (MSCs) can isolate from various tissues such as bone marrow and conjuncti...

[ 5 ] - Investigating the inhibitory effect of miR-34a, miR-449a, miR-1827, and miR-106b on target genes including NOTCH1, c-Myc, and CCND1 in human T cell acute lymphoblastic leukemia clinical samples and cell line

Objective(s): microRNAs are small non-coding molecules that regulate gene expression in various biological processes. T-cell acute lymphoblastic leukemia (T-ALL) is a malignancy accompanied with genetic aberrations and accounts for 20% of children’s and adult’s ALL. Notch signaling pathway dysregulation occurs in 60% of T-ALL cases. In the present study, we aimed to de...