ابوالفضل راد
مربی گروه بیوشیمی و تغذیه، مرکز تحقیقات سلولی و مولکولی، دانشگاه علوم پزشکی سبزوار، ایران
[ 1 ] - بررسی ارتباط ژن SOX2 و ژنهای تارگت مسیر Notch در سرطان مری
زمینه و هدف: سرطان مری ششمین عامل مرگ در جهان می باشد. با وجود درمان هایی همچون شیمی درمانی، رادیوتراپی و جراحی طول عمر بیماران بعد از شناسایی بسیار کوتاه دارد. از سویی شناسایی، پیشگیری و درمان بموقع نیاز به مشخص کردن مسیرهای مولکولی این نوع سرطان می باشد. در این مطالعه بمنظور مشخص شدن هر چه بیشتر مسیر رشد و نمو( development) با هدف قرار دادن فاکتور رونویسی SOX2 در یکی از رده های سلولی سرطان مر...
[ 2 ] - Maternal Side-Effects of Continuous vs. Intermittent Method of Entonox During Labor: A Randomized Clinical Trial
Labor pain is one of the most tiresome types of pain. So human has been seeking to allay this pain until now. Administration of a suitable agent such as Entonox during labor is very beneficial for childbirth outcomes. Entonox can be administered in two ways: intermittently and continuously. The aim of this study is to demonstrate whether continuous method is as safe as intermittent method? This...
[ 3 ] - Effect of EZH2 Inhibition on Colorectal Cancer Cells: an In Vitro Study
Recently, the epigenetic modifications have been recognized as a regulator of gene expression in various cancers. EZH2 gene is one the most important component of the PRC2 complex. Overexpression of EZH2 was identified in multiple cancers that considered more attractive the EZH2 role as an oncogene. Some studies report that EZH2 contributes to various aspects of colorectal cancer (CRC). However...
[ 4 ] - Maternal Side-Effects of Continuous vs. Intermittent Method of Entonox During Labor: A Randomized Clinical Trial
Labor pain is one of the most tiresome types of pain. So human has been seeking to allay this pain until now. Administration of a suitable agent such as Entonox during labor is very beneficial for childbirth outcomes. Entonox can be administered in two ways: intermittently and continuously. The aim of this study is to demonstrate whether continuous method is as safe as intermittent method? This...
[ 5 ] - Effect of Cinnamomum Verum Extract on the Amyloid Formation of Hen Egg-white Lysozyme and Study of its Possible Role in Alzheimer’s Disease
Introduction: Diagnosing and treating diseases associated with amyloid fibers remain a great challenge despite of intensive research carried out. One important approach in the development of therapeutics is the use of herbal extracts which are rich in aromatic small molecules. Cinnamomum verum extract (CE) contains proanthocyanidin and cinnamaldehyde, which have been suggested to be capab...
نویسندگان همکار