Gholamali Jelodar

Department of Physiology, Shiraz University, Shiraz,Iran

[ 1 ] - Saffron improved depression and reduced homocysteine level in patients with major depression: A Randomized, double-blind study

Objectives: A correlation between hyperhomocysteinemia, and depression has been reported. Saffron (Crocus sativus) is recommended for treatment of depression; hence, in this study the effect of co-administration of saffron and fluoxetine on plasma homocysteine and depression was evaluated. Material and methods: This was a 4-week randomized and double-blind clinical trial which was conducted fro...

[ 2 ] - Hydroalcoholic extract of flaxseed improves polycystic ovary syndrome in a rat model

Objective(s): Herbal medicines are an alternative choice for treatment or controlling of polycystic ovary syndrome (PCOS). Effect of hydroalcoholic extract of flaxseed was evaluated on ovarian hormones and histological changes of uterus and ovary in a PCOS-induced rat model.Materials and Methods: Twenty four rats divided into four groups including negative control, positive control, PCOS and tr...

[ 3 ] - بررسی اثر امواج مایکروویو نشت یافته از اجاق مایکروفر بر سلول های مغز استخوان موش صحرایی نر بالغ و نابالغ

Introduction: Increasing hematological diseases along with increased use of microwaves in different systems proposed possible correlation between them. Age of exposure to wave is also an important factor. This study was conducted to evaluate the effect of radiation leakaged from microwave oven on hemopoitic bone marrow cells at pre and post pubertal. Methods: Fourteen male mature (2 months old...

[ 4 ] - اثر عصاره هیدروالکلی میوه پنج انگشت بر باروری و سیکل جنسی در موش صحرایی پس از القای سندرم تخمدان پلی کیستیک با لتروزول

Background: Polycystic ovary syndrome (PCOS) is one of the most important endocrine disorders and a common cause of anovulation and infertility in women in the reproductive age. Vite xagnus castus is used as an alternative medicine for treatment of endocrine disorders in women. This study was conducted to evaluate the effects of hydroalcoholic extract of Vitex agnus castus on fertility and estr...

[ 5 ] - اثر عصاره‌ی هیدروالکلــــی گیــــاه خرگریــــو (Nectaroscordum tripedale) بر شاخص‌ های عملکردی کبد و کلیه در موش‌‌ های صحرایی نر دیابتی شده به وسیله‌ ی استرپتوزوتوسین

مقدمه: اثرات بعضی از گیاهان خانواده‌ی گیاه سوسنیان که عنصری از این خانواده است، بر کاهش گلوکز، لیپیدها و آنزیم‌های خون گزارش شده است. هدف از مطالعه‌ی حاضر، بررسی اثر عصاره‌ی هیدروالکلی خرگریو بر شاخص‌های عملکردی کبد و کلیه در موش‌های صحرایی نر دیابتی شده به وسیله استرپتوزوتوسین می‌باشد. مواد و روش‌ها: 40 سر موش صحرایی نر، به طور تصادفی به پنج گروه هشت تایی تقسیم شدند. گروه‌های اول و سوم ( شاهد ...

[ 6 ] - Vitamin E protects rat testis, eye and erythrocyte from oxidative stress during exposure to radiofrequency wave generated by a BTS antenna model

Background: Radio frequency wave (RFW) generated by mobile phones and wireless communication systems has been reported to cause adverse effects on reproductive function, vision and hematological parameters, possibly through oxidative stress. The aim of this study was to evaluate the effect of RFW generated bybase transceiver station BTS on oxidative stress in testis, eye and erythrocyte, and th...

[ 7 ] - Central administration of resistin into the paraventricular nucleus (PVN) produces significant cardiovascular responses

Introduction: Resistin, a complex multimeric structure which is secreted by adipose tissue and circulates in the blood, acts on the hypothalamus to increase sympathetic nerve activity, inhibit appetite and is associated with obesity, insulin resistance and cardiovascular disorders. In this study, we survey the cardiovascular effects of direct injection of resistin into specific cell group of th...

[ 8 ] - Extracts of the walnut leaf (Juglans regia L.) improved activity of sorbitol dehydrogenase in diabetic male rats

Introduction: Walnut leaf contains large amounts of antioxidants, phenolic compounds and flavonoids and the beneficial effect of these compounds in the treatment of diabetes has been shown. This study investigated the effect of cyclohexane and ethanol extract of walnut leaf on activity of sorbitol dehydrogenase (SDH) enzyme. Methods: Fifty- six adult male Sprague-Dawley rats were divided into s...

[ 9 ] - Silymarine extract improved plasma homocysteine, lipids and liver enzymes in hyperhomocysteinemic Non-alcoholic Steatohepatitis

Introduction: Silymarine extract is currently prescribed by some physicians for treatment of fatty liver disease. In the present study, the effect of administration of tablet containing silymarine extract on plasma homocysteine (Hcy), folate, vitamin B12 and liver enzymes activity in non-alcoholic steatohepatitis (NASH) was investigated. Materials and Methods: Seventy-four patients (40 female a...

[ 10 ] - Effect of Vitex agnus-castus fruits hydroalcoholic extract on sex hormones in rat with induced polycystic ovary syndrome (PCOS)

Introduction: PCOS is an important reproductive and endocrine disorder in women in the reproductive age. Present reports indicate that Vitex agnus-castus acts through hypothalamus-pituitary axis. This study was carried out to evaluate the effects of Vitex fruit hydroalcoholic extract on the alteration of sex hormones in a PCOS animal model. Methods: Following 14 days of monitoring of estrous...

[ 11 ] - Effects of radiation leakage from microwave oven on the body weight, thyroid hormones and cortisol levels in adult female mice

Introduction: Recent increase of endocrine disorders may be correlated to the increased exposure to electromagnetic fields from various instruments. Radiation leakage from microwave oven may be harmful for users. Ladies have the highest levels of contact with microwave ovens. This study was carried out to evaluate the effect of radiation leakage from microwave oven on body weight, cortisol a...

[ 12 ] - تاثیر امواج نشتی اجاق مایکروویو بر وزن بدن، هورمون‌های تیرویید، کورتیزول و لیپیدهای سرم در موش سوری نابالغ

Background: High-frequency electromagnetic field (EMF) is generated by differentsources such as radar installations, radio and television transmitters, medical microwave diathermy device and domestic use of microwave ovens. Radiation leakage of microwave oven may be harmful for users. Kids who are residing near their mothers may expose to electromagnetic field. This study was carrie...

[ 13 ] - Exposure to radiofrequency wave (RFW) generated by a base transceiver stations (BTS) antenna model affects learning and memory in female more than male rats

Background: Exposure to electromagnetic radiation may impair memory. This study was conducted to evaluate the effect of radiofrequency wave (hereafter referred to as RFW) on passive avoidance learning and memory in healthy males and females. Materials and Methods: Ten adult male and ten female Sprague-Dawley rats (230±20 gr) were randomly divided into four groups including two control groups (o...

[ 14 ] - Cardiovascular responses produced by resistin injected into paraventricular nucleus mediated by the glutamatergic and CRFergic transmissions within rostral ventrolateral medulla

Objective(s): Resistin, as a 12.5 kDa cysteine-rich polypeptide, is expressed in hypothalamus and regulates sympathetic nerve activity. It is associated with obesity, metabolic syndrome and cardiovascular diseases. In this study, we investigated the neural pathway of cardiovascular responses induced by injection of resistin into paraventricular nucleus (PVN) with rostr...