Sajad Maadani

Department of Pharmacognosy, Faculty of Pharmacy and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran

[ 1 ] - Effect of the methanolic extracts of different parts of Ferula assa-foetida on naloxone-induced withdrawal behavior in morphine-dependent mice

Objective: Ferula assa-foetida, a native species in Iran, is used for treatment of several diseases particularly for neurological disorders in Iranian Traditional Medicine. The aim of this study is to investigate the effect of methanolic roots, fruits, and aerial parts extracts of Ferula assa-foetida on withdrawal syndrome in morphine-dependent mice. Materials and Methods: Aerial parts, roots, ...

[ 2 ] - New benzodioxole compounds from the root extract of Astrodaucus persicus

There are many efforts for identification of natural compounds from dietary or medicinal plants. Young roots and aerial parts of A. persicus have been used as food additive or salad vegetable in some parts of Iran. In this study, different fractions of the root extract of A. persicus were subjected for isolation and purification of secondary metabolites. The methanol extract of the roots was fr...

[ 3 ] - Tocopherol Content and Fatty acid Profile of Different Iranian Date Seed Oils

Date is one of the world’s oldest food-producing plants wich has always played an important role in the economy and social life. Various researchers examined chemical composition and nutritional values of edible parts of dates while limited information about chemical composition and nutritional quality of date seed is available. In this study, fatty acid composition and total tocopherol content...

[ 4 ] - Investigation of Cytotoxic Activity in Four Stachys Species from Iran

   The aerial parts of Stachys laxa Boiss. and Buhse.from Siah-bishe in Mazandaran province, Stachys trinervis Aitch. and Hemsl. from Karaj in Alborz province, Stachys subaphylla Rech. F. and Stachys turcomanica Trautv. from Golestan province have been collected in May 2008. Total extracts were obtained through MeOH/H2O (80/20) and then partitioned between CHCl3, EtOAc and MeOH. These fractions...

[ 5 ] - Quantification of Gallic Acid in Fruits of Three Medicinal Plants

Triphala is a traditional herbal formulation consisting of dried fruits originating from three medicinal plants, namely Terminalia chebula, Terminalia bellirica and Phyllanthus embelica. It is used in folk medicine for the treatment of headaches, dyspepsia and leucorrhoea. There are some reports regarding Triphala"s pharmacological effects including its anti-cancer, radioprotective, hypocholest...

[ 6 ] - New benzodioxole compounds from the root extract of Astrodaucus persicus

There are many efforts for identification of natural compounds from dietary or medicinal plants. Young roots and aerial parts of A. persicus have been used as food additive or salad vegetable in some parts of Iran. In this study, different fractions of the root extract of A. persicus were subjected for isolation and purification of secondary metabolites. The methanol extract of the roots was fr...

[ 7 ] - Tocopherol Content and Fatty acid Profile of Different Iranian Date Seed Oils

Date is one of the world’s oldest food-producing plants wich has always played an important role in the economy and social life. Various researchers examined chemical composition and nutritional values of edible parts of dates while limited information about chemical composition and nutritional quality of date seed is available. In this study, fatty acid composition and total tocopherol content...

[ 8 ] - Investigation of Cytotoxic Activity in Four Stachys Species from Iran

   The aerial parts of Stachys laxa Boiss. and Buhse.from Siah-bishe in Mazandaran province, Stachys trinervis Aitch. and Hemsl. from Karaj in Alborz province, Stachys subaphylla Rech. F. and Stachys turcomanica Trautv. from Golestan province have been collected in May 2008. Total extracts were obtained through MeOH/H2O (80/20) and then partitioned between CHCl3, EtOAc and MeOH. These fractions...

[ 9 ] - Quantification of Gallic Acid in Fruits of Three Medicinal Plants

Triphala is a traditional herbal formulation consisting of dried fruits originating from three medicinal plants, namely Terminalia chebula, Terminalia bellirica and Phyllanthus embelica. It is used in folk medicine for the treatment of headaches, dyspepsia and leucorrhoea. There are some reports regarding Triphala"s pharmacological effects including its anti-cancer, radioprotective, hypocholest...

[ 10 ] - بررسی تغییرات فصلی اسانس گیاه اکلیل کوهی (L. Rosmarinus officinalis)

مقدمه: گیاه اکلیل کوهی یکی از گیاهان واجد اسانس خانواده نعناعیان2 است. این گیاه بومی منطقه مدیترانه و خاور نزدیک بوده و در حال حاضر تقریباً در همه کشورها به عنوان گیاه دارویی و زینتی کشت می‌شود. این گیاه از زمان‌های قدیم به عنوان ادویه و دارو استفاده می‌شد. هدف: با توجه به اینکه عوامل محیطی و ژنتیکی بر نوع و میزان اسانس این گیاه اثر می‌گذارند، هدف این پژوهش بررسی تغییرات فصلی اسانس گیاه اکلیل...

[ 11 ] - بررسی بهترین روش استخراج ترکیبات فنلی موجود در گیاه سرخارگل

مقدمه: سرخارگل گیاهی است که از دیرباز در طب سنتی مورد مصرف بوده است. امروزه تحقیقات وسیعی روی این گیاه انجام شده و مشخص شده است که این گیاه باعث تحریک سیستم ایمنی بدن می‌شود. گیاه شامل ترکیبات متعددی مثل فلاونوئیدها، ترکیبات فنلی و ایزوبوتیل آمیدها است. ترکیبات فنلی یکی از مهم‌ترین دسته ترکیباتی هستند که اثرات محرک سیستم ایمنی آن‌ها اثبات شده است. بنابراین تعیین روشی برای استخراج بهینه این مواد...

[ 12 ] - Effect of Rubia tinctorum L. Extractson Carrageenan-Induced Paw Edema in Rats

Background: Inflammation is a dynamic process that is elicited in response to various harmful stimulantsthat may threaten the well-being of the host. Herbs have been traditionally used as anti-inflammatory agents since very early times. Rubia tinctorum L. is one of these herbs that havebeen used for treating inflammatory diseases in Iranian traditional medicine. Objective: This study aims at c...

[ 13 ] - Composition of the Essential Oils of Thymus deanensis Celak Var. deanensis from Different Regions of Iran

Background: Thymus deanensis is a known aromatic plant which grows widely in Iran and many mediterranean regions. In previous studies composition of essential oils of many species of Thymus genus reported which they were rich of phenols like Thymol and Carvacrol. Methods: Water distilled essential oils from aerial parts of Thymus deanensis var. deanensis from three different localities in Iran...

[ 14 ] - Anti-inflammatory Effect of Thymus kotschyanus Boiss. & Hohen. Extract on Rat’s Hind Paw Edema Induced by Carrageenan

Background: Advantages of herbal drugs have been known to human being for many years and they have been used for treatment of many diseases. Nowadays, inflammation is known to be one of the basic pathologic causes of the diseases. Objective: In this study the anti-inflammatory effect of Thymus kotschyanus Boiss & Hohen was investigated. Methods: Forty two Wistar rats were used in three divide...

[ 15 ] - Could Melissa Officinalis Extract Restore Streptozotocin-Induced Spatial Memory Impairment in Rats?

Introduction: Alzheimer disease is a progressive and irreversible neuropsychiatric disorder. Melissa Officinalis improves anxiety and clinical dementia symptoms caused by AD therefore, the purpose of the present study was to evaluate the effect of Mellisa extract on spatial memory deficit induced by STZ in MWM examination of male wistar rats. Methods: In the present study, 112 male wista...

[ 16 ] - Capparis spinosa: a comparative study of raw and processed fruits

Background: Capparis spinosa is used in different countries for prevention and treatment of various diseases. Its fruits are usually used in processed form especially with vinegar. Objective: The aim of the present study was investigating the effect of processing on some phytochemical constituents and biological activities of C. spinosa. Methods: The fruits were processed with grape vinegar. To...