Hossein Sadeghi

Department of Pharmacology, Faculty of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran

[ 1 ] - Hepatoprotective effect of Rosa canina fruit extract against carbon tetrachloride induced hepatotoxicity in rat

Objective: The present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of Rosa canina (R. canina) against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Methods: Male Wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (CCl4), R. canina 250, 500, and 750 mg/kg + CCl4 and R. canina ...

[ 2 ] - Hepatoprotective activity of aerial parts of Otostegia persica against carbon tetrachloride-induced liver damage in rats

Objective: To evaluate the hepatoprotective properties of Otostegia persica (O. persica) ethanol extract on carbon tetrachlo‌‌ride-induced liver damage in rats. Materials and Methods: Fifty adult male Wistar rats were randomly divided into five groups. Group I served as normal control and was given only olive oil intraperitoneally (i.p.). Group II, III, IV, and V were administered CCl4 mixed wi...

[ 3 ] - Effect of Fluvoxamine on Carrageenan-Induced Paw Edema in Rats Evaluation of the Action Sites

The present study was designed to explore the anti-inflammatory effect of fluvoxamine, as a selective serotonin reuptake inhibitor (SSRI) anti-depressant, on carrageenan-induced paw edema in more details. At first, fluvoxamine was administered intra-peritoneally (2.5, 12.5, 25 and 50 mg Kg-1) 30 min before the subplantar injection of carrageenan. Fluvoxamine was also injected intra-peritoneally...

[ 4 ] - Effect of Fluvoxamine on Carrageenan-Induced Paw Edema in Rats Evaluation of the Action Sites

The present study was designed to explore the anti-inflammatory effect of fluvoxamine, as a selective serotonin reuptake inhibitor (SSRI) anti-depressant, on carrageenan-induced paw edema in more details. At first, fluvoxamine was administered intra-peritoneally (2.5, 12.5, 25 and 50 mg Kg-1) 30 min before the subplantar injection of carrageenan. Fluvoxamine was also injected intra-peritoneally...

[ 5 ] - «بررسی تمثیلات مشترک میان مثنوی های عطّار و مثنوی معنوی مولوی»

«تمثیل» یکی از شیوه های بیانی است که از دیرباز برای تبیین و تفهیم آموزه­های دینی، اخلاقی، عرفانی و ... در جامعۀ انسانی به کار رفته است. بزرگان ادب عرفانی ما نیز، از جمله سنایی، عطّار، مولوی و ... از این شگرد برجسته در تفهیم اصول عرفانی و اندیشه­های متعالی خود بهره برده­اند و نکات ظریف و عالی غیر محسوس را به زبانی ساده و محسوس برای مخاطبان و خوانندگان آثار خود باز گفته­اند. مقالۀ حاضر ضمن تعریف و...

[ 6 ] - Drying of Matricaria recutita Flowers in Vibrofluidized Bed Dryer: Optimization of Drying Conditions Using Response Surface Methodology

Drying of Matricaria recutita flower was investigated experimentally in a VibroFluidized Bed Dryer (VFBD). The aim of the present work was to optimize the best operating conditions for the drying of Matricaria recutita flower in the VFBD based on experimental design techniques. Response Surface Methodology (RSM) and Central Composite Design (CCD) based on 4-variable with 5-level have been e...

[ 7 ] - comparison of the effect of omeprazole,es omeprazole and lanzoprazole on treatment of gastroesophageal reflux disease referred children aged 2 to 24 months to shahid- mofatteh clinic of yasuj-2015

Background and objective:Gastroesophageal reflux is one of the most common esophageal disordersat all age groups, especially in children, due to the transient slackness of sphincter of the lower esophagus, which results in impairment in the quality of life of the infant.Various studies have shown that proton pump inhibitors have a beneficial effect on the treatment of gastroesophageal reflux di...

[ 8 ] - Anticancer activity of Astragalus ovinus against 7, 12 dimethyl benz (a) anthracene (DMBA)-induced breast cancer in rats

Objective: Some species of Astragalus are used for the treatment of various types of cancer. The present study was designed to evaluate the anticancer potential of Astragalus ovinus extract (AOE) against DMBA-induced breast carcinoma in rats. Materials and Methods: The anti-tumor and antioxidant effects of AOE were evaluated against DMBA...