In somatic hybrids between fibroblast microcells and rat hepatoma cells, tissue-specific extinguisher 1 (TSE1), localized to mouse chromosome 11, extinguishes the expression of tyrosine aminotransferase and phospho(enol)pyruvate carboxykinase. Recently, it was demonstrated that TSE1 corresponds to R1 alpha, a regulatory subunit of protein kinase A. Here, we have analyzed whether R1 alpha could ...

i=1 H(ri); (5) HΨ(r1, r2, · · · ) = EΨ(r1, r2, · · · ). (6) (Note: For simplicity, unless necessary, we often write r as r.) Since there is no interaction between particles, the Schrodinger equation is separable. Assume Ψ(r1, r2, · · · , rN ) = φ(r1)φ(r2) · · ·φ(rN ), (7) then Hφαi(ri) = εαiφαi(ri), i = 1, 2, · · ·N. (8) Manybody eigenstate is a product of 1-particle states, Ψα1,α2,···(r1, r2, ...

A specific polyclonal Ab against the N-terminal domain of corticotropin-releasing factor (CRF) receptor, type 1 (CRF-R1), was employed to an immunohistochemical analysis of the spleen from naive mice and mice exposed to an immune challenge. Cell types stained with anti-CRF-R1 Ab were identified by their nuclear shapes and colocalization with the cell type-specific markers ER-MP58, ER-MP20, Moma...

Advanced glycation endproducts (AGE) contribute to kidney disease due to diabetes or aging by means of mesangial cell (MC) receptors, such as the receptor for AGE (RAGE), which promote oxidant-stress-dependent NF-kappaB activation and inflammatory gene expression. MC also express scavenger receptors SR-I and SR-II and AGE receptors 1, 2, and 3 (AGE-R1, -R2, and -R3), some of which are linked to...

Antimutagenic substances were purified from a culture supernatant of Lactobacillus plantarum KLAB21 cells isolated from kimchi, a Korean traditional fermented vegetable, and their characteristics were investigated. The antimutagenic substances were separated into two fractions by DEAE-cellulose ion-exchange column chromatography, which were designated the R1 and R2 fractions. The R1 fraction wa...

Streptococcus pneumoniae is a microorganism that frequently causes serious infections in children, the elderly, and immunocompromised patients. We studied whether the specific intracellular adhesion molecule-grabbing nonintegrin R1 (Sign-R1) receptor, involved in the uptake of capsular polysaccharides (caps-PS) by antigen-presenting cells, is necessary for the antibody response to pneumococcal ...

Let R = ⊕ g∈GRg be a G-graded ring. It is well known (see e.g. [D], [M1], [N], [NRV], [NV]) that in the study of the connections that may be established between the categories R-gr of graded R-modules and R1-mod (1 is the unit element of G), an important role is played by the following system of functors : (−)1 : R-gr → R1-mod given by M 7→ M1, where M = ⊕ g∈GMg is a graded left R-module, the i...

We report on the separate PCR cloning and subsequent expression and purification of the large (R1) and small (R2) subunits from equine herpes virus type 4 (EHV-4) ribonucleotide reductase. The EHV-4 R1 and R2 subunits reconstituted an active enzyme and their abilities to complement the R1 and R2 subunits from the closely related herpes simplex virus 1 (HSV-1) ribonucleotide reductase, with the ...