Chloride Intracellular Channel 4 Is Required for Maturation of the 1 Cerebral Collateral Circulation 2 3 4 Jennifer L. Lucitti, Natalie J. Tarte, and James E. Faber 5 6 Department of Cell Biology and Physiology and the McAllister Heart Institute, 7 University of North Carolina at Chapel Hill 8 9 10 Running title: CLIC4 regulates maturation of collateral 11 12 Corresponding Author: 13 14 James E...

This paper presents a dynamic portfolio choice model to analyze the liquidity premium necessary to compensate an investor for the adverse price impact of trading. By calibrating the model to empirically reasonable parameter values, we generate a plausible liquidity premium. Specifically, the premium is an increasing, concave function of price impact. It increases with the investor’s initial wea...

Recent trends in medical education emphasize the importance of producing well-rounded graduates who not only possess a sufficient fund of medical knowledge but who can think clearly and deeply. Unfortunately, many medical educators struggle with what exactly it means to “think” and do not know where to begin when asked to teach “thinking.” We believe the book Making Thinking Visible, though wri...

Department of Radiation Oncology, Box 3085, Duke University Medical Center, Durham, NC 27710, USA *Author for correspondence: Tel.: +1 919 668 7336; Fax: +1 919 668 7345; [email protected] The incidence of esophageal cancer has increased dramatically over the last few decades [1,2]. Despite substantial advances in surgery, chemotherapy and radiation therapy, mortality rates for this disease ...

From the Department of Orthopedic Surgery, Sri Ram Murti Samarak Institute of Medical Sciences, Bhojipura, Bareilly, Uttar Pradesh, India. Address correspondence to: Dr. Yasir S. Siddiqui, Department of Orthopedic Surgery, PO Box 71, Sri Ram Murti Samarak Institute of Medical Sciences, Bhojipura, Bareilly, Uttar Pradesh, India. Tel. +919 (83) 7343400. Fax. +915 (71) 2702758. E-mail: yassu98@gma...