Despite recent advances in therapeutic and diagnostic approaches, coronary artery disease (CAD) and its related cardiac disorders represent the most common cause of death in the United States. Nuclear myocardial perfusion imaging (MPI) technologies play a pivotal role in the diagnosis and treatment design for CAD. Recently, in order to develop improved MPI agents for diagnosis of CAD, (99m)Tc-[...

  Introduction: Radio-guided parathyroid surgery along with other minimally invasive surgeries constitutes the main surgical treatment procedures for different kinds of hyperparathyroidism.  In this article we have reported our experience of radio-guided parathyroid surgery using Tc-99m sestamibi. Methods: Ten patients with hyperparathyroidism included in our study. ...

UNLABELLED This study was designed to compare the tracer kinetics between 99mTc-sestamibi and 99mTc-tetrofosmin in a heterogeneous group of 24 patients admitted for routine perfusion imaging. METHODS Twelve patients were studied with 99mTc-tetrofosmin and 12 with 99mTc-sestamibi. In each group, six patients had a low likelihood for coronary artery disease, and six patients had angiographicall...

We report the case of a 71-year-old woman who was referred to our institute with a solid nodule in the right thyroid lobe and hypercalcemia. Ultrasound revealed a well-vascularized right thyroid nodule that was identified as a cold area by (99m)Tc-sodium pertechnetate scan. Fine-needle aspiration showed a follicular lesion and blood tests revealed hypercalcemia and hyperparathyroidism. A (99m)T...

introduction: we aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected cad is different from that of intravenous (iv) dipyridamole using tc-99m mibi myocardial perfusion gated spect. methods: eighty-nine patients (17 m / 72 w; 61 ± 10 years) were enrolled in this study. the patients underwent a dipyridamole stres...

UNLABELLED Gaucher's disease is a lysosomal storage disorder due to a genetically transmitted deficiency of the enzyme glucocerebrosidase. In the most common form of the disease (type 1), accumulation of glucosylceramide in the reticuloendothelial cells of liver, spleen, and bone marrow leads to visceromegaly, anemia, thrombocytopenia, and osteopenia. Skeletal manifestations secondary to infilt...

mammography remians the procedure of choice in screening asymptomatic women for breast cancer. however, in patients with symptoms, other types of imaging play an important role in the detection of malignancies. the high cost and lack of availability of pet and mri largely precludes the use in this patient population. ti-201 is nbt the imaging agent of choice because of its wash-out and redistri...

The aim of this study is to evaluate whether the technetium-99m sestamibi ((99m)Tc-MIBI) single photon emission computed tomography (SPECT) characteristics of pituitary adenomas might be correlated with cavernous sinus invasion, proliferative potential or the multidrug-resistance (MDR-1) gene product P-glycoprotein (Pgp) expression in pituitary adenomas. Fifteen patients with pituitary adenomas...