The concept of net-zero carbon emissions has emerged from physical climate science. However, it is operationalized through social, political and economic systems. We identify seven attributes net zero, which are important to make a successful framework for action. highlight the urgency emission reductions, need be front-loaded, coverage all sources, including currently difficult ones. emphasize...

The search for ideal predictors of successful extubation or “liberation” from mechanical ventilation has been a subject of constant investigation for over half a century. Initial investigations were spurred by the need to determine adequate reversal of paralytic agents after general anesthesia, sufficient to allow sustained spontaneous ventilation and permit extubation.1,2 It is notable that th...