The anatomy of a child’s bone may be divided into its basic components: the epiphysis, physis, metaphysis, and diaphysis. An appreciation of the growth and function of each structure is critical whenever a clinician encounters pathologies in the pediatric skeleton. The following review discusses the differential diagnoses of abnormal secondary centers of ossification (SCO), a topic which is inf...

polyclonal anti-thymocyte globulin (atg) is used as an immunosuppressive agent in the treatment of aplastic anemia (aa). serum sickness is a recognized side effect of atg. we observed abnormal skin manifestation in patient with aplastic anemia who had been treated with atg. we conclude that abnormal immune function caused by aplastic anemia and atg and corticosteroids may aggravate the signs of...

Rehabilitation of children with unilateral cerebral palsy has been progressed and improved their body function and structure, activities and participation of these children dramatically and increased their quality of life. Despite this progress, we still need improvement of intervention that address and focus on whole body movement and function during daily activities to change the habitual and...

An understanding of metabolic pathways based solely on biochemistry textbooks would underestimate the pervasive role of metabolism in essentially every aspect of biology. It is evident from recent work that many human diseases involve abnormal metabolic states--often genetically programmed--that perturb normal physiology and lead to severe tissue dysfunction. Understanding these metabolic outli...