Using human embryonic fibroblast (HEF) and HEp-2 cell cultures, adenoviruses were isolated from 989 (3.7%) out of 26,793 pediatric patients with ARI in Yamagata, Japan from January, 1986 to December, 1991. All isolates were identified as types 1 (Ad1)-6 and no other serotypes were identified. Epidemiologic feature was different depending on the subgenus group. Ad1, 2, 5 and 6 (group C) were end...

BACKGROUND & AIMS There have been many studies on plasma butyrylcholinesterase in liver dysfunction. However, no data is available about acetylcholinesterase in human cirrhosis, although profound changes have been described in cirrhotic rat models. METHODS Human serum and liver acetylcholinesterase and its molecular forms were determined enzymatically, after butyrylcholinesterase immunodeplet...

Alzheimer disease (AD) diderita oleh 30-35 juta penderita di dunia dan diperkirakan akan meningkat hingga 400% dalam 30 tahun kedepan Indonesia. Salah satu obat yang telah diterima untuk pengobatan AD diisolasi dari tanaman Galanthus nivalis berperan sebagai inhibitor acetylcholinesterase (AChe), galantamine, memiliki efek singkat. Penerimaan terhadap senyawa herbal semakin luas karena kebutuha...

Introduction: Finding herbs with promising effects to prevent or postpone Alzheimer Disease (AD) is highly demanded. The present study aimed at clarifying plausible effects and related mechanism(s) of Zataria Multiflora Essential Oil (ZMEO) against memory impairment in a rat model of the AD. Methods: Forty male adult rats were categorized into four groups and treated as follows: 1. The Negativ...

Pharmacognosy Research,2022,14,1,45-52.DOI:10.5530/pres.14.1.8Published:December 2021Type:Original ArticleAuthors:Bruna Yuka Koide da Silva, Aniele Silva Neves Lopes, Paulo José Sousa Maia, Josiana Moreira Mar, Laiane Souza Edgar Aparecido Sanches, Geone Maia Corrêa, Jaqueline de Araújo Bezerra, and Dominique Fernandes Moura do Carmo Author(s) affiliations:Bruna Silva1, Lopes1, Maia2, Mar3, Sil...

The aim of this work was to reuse a fish processing waste, shrimp head powder (SHP), for the production prodigiosin (PG) via microbial technology and assess its potential bioactivities. PG produced in 12 L-bioreactor system, highest productivity 6310 mg L?1 achieved when Serratia marcescens CC17 used fermentation novel designed medium (6.75 L) containing 1.5% C/N source (SHP/casein = 9/1), 0.02...

Notwithstanding the functional role that the aggregates of some amyloidogenic proteins can play in different organisms, protein aggregation plays a pivotal role in the pathogenesis of a large number of human diseases. One of such diseases is Alzheimer's disease (AD), where the overproduction and aggregation of the β-amyloid peptide (Aβ) are regarded as early critical factors. Another protein th...

The short and long term effects of chromium toxicity on brain catecholamines and acetylcholinesterase levels were investigated. Rats were injected daily with varying amounts of chromium. The short term (2 h) administration of chromium (8 mmol/kg) reduced catecholamines level of cerebellum, mid-brain and brain-cortex by 22.8, 19.4 and 21.2% respectively. Acetylcholinesterase activity was also re...