Tahoora Shomali
Division of Pharmacology and Toxicology, Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
[ 1 ] - Protective effect of Urtica dioica leaf hydro alcoholic extract against experimentally-induced atherosclerosis in rats
Objective: Finding compounds that could be used for prevention of atherosclerosis (AS) is highly desired. The present study evaluated the protective effects of Urtica dioica (UD, commonly known as stinging nettle) leaf ethanolic extract against high-fat diet-induced AS in rats. Materials and Methods: In this study, 40 male adult Sprauge-Dawley rats were randomly allocated to 4 equal groups and ...
[ 2 ] - Effect of Zataria multiflora essential oil on immune responses and faecal virus shedding period in broilers immunized with live Newcastle disease vaccines
Zataria multiflora essential oil possesses immunomodulatory effects and the present study investigatesits effect on immune responses to live Newcastle disease (ND) vaccines and faecal shedding period ofvaccine strain virus in chickens. One hundred and eighty chickens from both sexes were divided into 6 equalgroups: group 1: unvaccinated, group 2: vaccinated (B1 vaccine followed by La Sota 10 da...
[ 3 ] - اثرات محافظتی بر استخوان متعاقب تجویز عصاره الکلی گیاه گلدر (Otostegia persica) در موش‌های دیابتی شده توسط استرپتوزوتوسین: مطالعه هیستومورفومتری
زمینه مطالعه: داروهای گیاهی اخیراً برای درمان دیابت مورد توجه قرار گرفته اند. یکی از عوارض دیابت پوکی استخوان بوده و خطر شکستگی استخوان را در بیماران دیابتی افزایش می‌دهد. گیاه گلدر با داشتن خصوصیات آنتی اکسیدانی و کاهش دهنده قند خون به عنوان عامل ضد دیابتی معرفی شده است. هدف: این مطالعه بررسی اثرات بالقوه محافظتی بر بافت استخوان توسط عصاره الکلی گیاه گلدر در موش‌های دیابتی می‌باشد. روش‌کار: ...
[ 4 ] - Expression of HCA2 Receptors in Femoral Epiphysis and Metaphysis of Rats with Dexamethasone-Induced Osteoporosis
The present study describes the changes in expression of hydroxy- carboxylic acid receptor 2 (HCA2 receptor) in femoral epiphysis and metaphysis of rats with glucocorticoid-induced osteoporosis (GIO). 16 growing male Sprauge dawley rats were randomly divided into two equal groups consisting of normal control and rats that were rendered osteoporotic by receiving 0.1 mg/kg/day dexamethasone throu...
[ 5 ] - Achillea Millefolium L. Hydro- Alcoholic Extract Protects Pancreatic Cells by Down Regulating IL- 1β and iNOS Gene Expression in Diabetic Rats
Interleukin-1β (IL-1β) has a role in β- cell destruction in autoimmune diabetes by stimulating the expression of inducible nitric oxide synthase (iNOS) that generates the free radical nitric oxide. We aimed to investigate the effect of Achillea millefolium L, as a traditional hypoglycemic agent, on IL-1β and iNOS gene expression of pancreatic tissue in the STZ- induced diabetic rats. Forty adul...
[ 6 ] - شناسایی و تعیین مکان گیرنده‌های HCA2 در دستگاه ادراری موش صحرایی نر به روش ایمونوهیستوشیمی
زمینه و هدف: گیرنده HCA2 به‌عنوان هدف داروی مهم کاهنده لیپیدهای سرمی، یعنی نیاسین، بسیار موردتوجه است. این مطالعه به تعیین حضور و نیز شناسایی نوع سلول‌های بیان‌کننده این گیرنده در بافت‌های مختلف دستگاه ادراری موش صحرایی نر شامل کلیه، میزنای، مثانه و میزراه (در پنیس) می‌پردازد. روش بررسی: در این مطالعه تجربی از 6 سر موش صحرایی بالغ از نژاد Wistar استفاده شد. مقاطع بافتی از بخش‌های فوق‌الذکر تهیه...
[ 7 ] - Neuroprotective Effect of Zataria Multiflora Essential Oil on Rats With Alzheimer Disease: A Mechanistic Study
Introduction: Finding herbs with promising effects to prevent or postpone Alzheimer Disease (AD) is highly demanded. The present study aimed at clarifying plausible effects and related mechanism(s) of Zataria Multiflora Essential Oil (ZMEO) against memory impairment in a rat model of the AD. Methods: Forty male adult rats were categorized into four groups and treated as follows: 1. The Negativ...
[ 8 ] - Gastro-protective effect of Biebersteinia multifida root hydro-methanolic extract in rats with ethanol-induced peptic ulcer
Objective: Biebersteinia multifida is one of the native plants of Iran and its root is used in folk medicine. This study aimed to evaluate the gastro-protective effect of the hydro-methanolic extract of this plant's roots against ethanol-induced gastric ulce...
[ 9 ] - Zataria multiflora, broiler health and performance: a review
Zataria multiflora Boiss. (ZM) from Lamiaceae family, is an herb native to Iran, Pakistan, and Afghanistan with a history of use both as a condiment and a traditional medicine. The herb and/or its preparations have also shown promising effects in modern pharmacological studies. With regard to the importance of reducing synthetic drug administration both as growth promoters and therapeu...
[ 10 ] - Eryngium Bungei Boiss Extract Has Hepatoprotective Effect Against Liver Damage Induced by Acetaminophen in Rats: Novel Antioxidant and Anti-Inflammatory Effects
Background: Acetaminophen-induced toxicity is a common cause of acute liver failure. This study investigated the hepatoprotective effects of Eryngium bungei Boiss (EB) extract against the hepatotoxicity in rats. Methods: Thirty adult male rats were randomly assigned to five groups, with free access to water and food. They were treated as follows: Group 1 (negative controls): distilled water ...
[ 11 ] - اثرات تجویز فلورفنیکل خوراکی روی برخی شاخصهای خونشناختی قزلآلای رنگین کمان (Oncorhynchus mykiss) تحت چالش با عوامل استرپتوکوکوزیس/ لاکتوکوکوزیس
زمینۀ مطالعه: آنتی بیوتیک‌ها می‌توانند وضعیت فیزیولوژیک و سیستم ایمنی میزبان را دستخوش تغییر نمایند و بکارگیری شاخصهای خونی نشانگر مناسبی برای پایش آن‌هاست. هدف: مطالعه تغییرات شاخصهای خونشناختی ماهی قزلآلای رنگین کمان تحت چالش با عوامل استرپتوکوکوزیس/ لاکتوکوکوزیس در پی مصرف فلورفنیکل خوراکی. روش‌کار: بدین منظور، تعدادی ماهی (5/7 ± 55 گرم) در یک بلوک کاملاً تصادفی در 6 تیمار و 3 تکرار شامل ...
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