نتایج جستجو برای: adrafinil analogues

تعداد نتایج: 28279  

Journal: :Acta Biochimica Polonica 2001

Let $(u_n)$ be a sequence of fuzzy numbers.  We recover the slow oscillation of $(u_n)$ of fuzzy numbers from the Ces`{a}ro summability of its generator sequence and some additional conditions imposed on $(u_n)$. Further, fuzzy analogues of some well known classical Tauberian theorems for Ces`{a}ro summability method are established as particular cases.

Afshin Zarghi, L Erfani Jabarian MH Houshdar Tehrani

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.

A Mostafavirad A Samiei E Mohammadian F Hadizadeh MR Jaafari

Four conformationally restricted analogues of pentamidine were prepared. Then, different concentrations (0.039, 0.078, 0.156, 0.312 and 0.625 mg/mL) of each compound and two positive controls (amphotericin B and pentamidine, 0.625 mg/mL), one negative control (culture medium) and one solvent control (DMSO) were prepared and placed in 24-well plates containing 50000 parasite per well. Promastigo...

Journal: :The New England journal of medicine 2005
Irl B Hirsch

N Engl J Med 2005;352:174-83. Copyright © 2005 Massachusetts Medical Society. he discovery of insulin more than 80 years ago is considered one of the greatest medical breakthroughs of the 20th century. 1 The first commercial insulin preparations contained numerous impurities and varied in potency from lot to lot by as much as 25 percent. Manufacturing techniques improved rapidly, however, which...

Journal: :iranian journal of basic medical sciences 0
seyed adel moallem pharmaceutical research center, mashhad university of medical sciences, mashhad, iran 2 medical toxicology research center, mashhad university of medical sciences, mashhad, iran 3 department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran mohsen imenshahidi department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran narges shahini department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran ahmad reza javan department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran mohsen karimi department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran mona alibolandi biotechnology research center, mashhad university of medical sciences, mashhad, iran

objective(s): nowadays, cox- 2 inhibitors such as valdecoxib are removed from the market because of their cardiovascular toxicity and their potential to increase the risk of strokes. in response to this, medicinal chemists have attempted to synthesize new classes of cox-2 inhibitors.   materials and methods: in this study, three novel analogues of thiazolidin-4-ones derivatives 2a-c were synthe...

Journal: :The Journal of Cell Biology 1988
G P Vigers M Coue J R McIntosh

We have synthesized three new fluorescent analogues of tubulin, using fluorescein or rhodamine groups attached to N-hydroxy-succinimidyl esters, and have partially characterized the properties of these analogues. We have also further characterized the tubulin derivatized with dichlorotriazinyl-aminofluorescein that has previously been used in this and other laboratories. Our results show that a...

Journal: :Bioorganic & medicinal chemistry 2003
Gabriel Navarrete-Vázquez Lilián Yépez Alicia Hernández-Campos Amparo Tapia Francisco Hernández-Luis Roberto Cedillo José González Antonio Martínez-Fernández Mercedes Martínez-Grueiro Rafael Castillo

Albendazole (Abz) and Mebendazole (Mbz) analogues have been synthesized and in vitro tested against the protozoa Giardia lamblia, Trichomonas vaginalis and the helminths Trichinella spiralis and Caenorhabditis elegans. Results indicate that compounds 4a, 4b (Abz analogues), 12b and 20 (Mbz analogues) are as active as antiprotozoal agents as Metronidazole against G. lamblia. Compound 9 was 58 ti...

2008
JASPER V. STOKMAN

Hyperbolic beta integrals are analogues of Euler’s beta integral in which the role of Euler’s gamma function is taken over by Ruijsenaars’ hyperbolic gamma function. They may be viewed as (q, q̃ )-bibasic analogues of the beta integral in which the two bases q and q̃ are interrelated by modular inversion, and they entail q-analogues of the beta integral for |q| = 1. The integrals under considerat...

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