This minireview will provide a perspective on new developments and concepts related to biomarker applications for vaccines. In the context of preventive vaccines, biomarkers have the potential to predict adverse events in select subjects due to differences in genetic make-up/underlying medical conditions or to predict effectiveness (good versus poor response). When expanding them to therapeutic...

Pharmaceutical companies and health agencies within the U.S. government assure medical consumers that vaccines are safe and the benefits far outweigh the risks. Yet the Food and Drug Administration (FDA) receives 11,000 reports of serious adverse reactions, including death, to vaccines annually. The FDA estimates that less than 10% of serious adverse events are reported. Grieving parents of oth...

The number of vaccines available and included as part of the national immunization schedules, has increased significantly over the past few decades. This impacts on patient/parent compliance and creates a challenge for health care providers for implementation of schedules necessitating training and infrastructure improvements. Use of combination rather than component vaccines offers advantages ...

background: tins research was conduced to estimate the positive predictive value of physicians at kerman emergency services for traumatic patients who referred to radiology department of kerman hospital in 2001. methods: this study was a cross-sectional study and carried out on 353 patients. a questionnaire was used as a research instrument. results: three radiologists reported the films separa...

background: renal failure is an important adverse effect of drug poisoning. determining the prevalence and etiology of this serious side effect could help us find appropriate strategies for the prevention of renal failure in most affected patients. objectives: the present study is aimed to identify drugs that induce renal failure and also to find the prevalence of renal failure in patients refe...

abstract background peripheral blood vessels, due to availability are used for many years in cancer patients, however in patients with potentially harmful drugs to skin (vesicant drugs) or difficult accessibility to vessels, the use of implantable port (totally implantable venous access port-tivap)devices with central vascular access are important.  materials and methods in this retrospective s...

abstract background some researches have shown the association between iron deficiency and migraine headache in adults. the aim of present study was to evaluate efficacy of ferrous sulfate treatment on migraine headaches of 5-15 years old migraineur children with iron deficiency. materials and methods in a quasi- experimental study, monthly frequency, severity, duration and disability of headac...

introduction: endometrial cancer is the most common pelvic malignancy in women. approximately 7,000 women die from this disease every year. although most patients can be treated with appropriate therapies, there is insufficient data regarding the choice of the best adjuvant therapy after a surgical procedure in advanced endometrial cancer cases. it seems that radiotherapy or chemotherapy alone ...