نتایج جستجو برای: alpha lipoic acid
تعداد نتایج: 916211 فیلتر نتایج به سال:
Background: Today, infertility is a problem that affects about 15% of couples due to male factors, female factors or both. High levels of oxidative stress, because of an imbalance between the reactive oxygene species and the antioxidant capacity, have been repeatedly reported in infertile men, which can have a destructive effect on the spermatogenesis process. Antioxidant treatment can improve ...
Introduction: Diabetes is a common metabolic disease, which leads to diabetic peripheral neuropathy. Peripheral neuron damage result in Nav1.3 elevations. Exercise training has beneficial role in diabetes management and peripheral neuropathy. Alpha lipoic acid (ALA) is a powerful biological antioxidant. However, the role of exercise training and ALA on Nav1.3 are not well understood. The aim of...
Introduction: Activation of NLRP-3 Inflammasome is considered an indicator of chronic inflammation in type 2 diabetes. Regular exercise training along with antioxidants supplements can control inflammation. The aim of the present study was to investigate the effect of training with different intensity and alpha lipoic acid supplement on pancreatic NLRP-3 expression in diabetic rats. Methods: ...
Mardonnes J, Segovia N, Hederra A, Alcaino F. Influence of sulfasuxidine on the effect of alpha lipoic or thioctic acid on the voluntary alcohol intake of rats depleted of factor N1. Acta Physiol Lat Am. 1953;3(2-3):140-3. PMID: 13138254 Abstract Mardonnes J, Segovia N, Alcaino F, Hederra A. Effect of synthetic thioctic or alpha lipoic acid on the voluntary alcohol intake of rats. Science. 1954...
Accumulating data demonstrated that hypercholesterolemia and oxidative stress play an important role in the development of atherosclerosis. In the present study, a protective activity of alpha-lipoic acid; a metabolic antioxidant in hypercholesterolemic-induced animals was investigated. Eighteen adult male New Zealand White (NZW) rabbit were segregated into three groups labelled as group N, HCD...
Atherosclerotic plaque contains apoptotic endothelial cells with oxidative stress implicated in this process. Vitamin E and alpha-lipoic acid are a potent antioxidant combination with the potential to prevent endothelial apoptosis. Regular exercise is known to increase myocardial protection, however, little research has investigated the effects of exercise on the endothelium. The purpose of the...
Diabetes is a common metabolic disorder that is usually accompanied by increased production of reactive oxygen species or by impaired antioxidant defenses. Importantly, oxidative stress is particularly relevant to the risk of cardiovascular disease. Alpha-lipoic acid (LA), a naturally occurring dithiol compound, has long been known as an essential cofactor for mitochondrial bioenergetic enzymes...
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