in critically ill infants and children, intravascular (iv) access is sometimes very difficult. in such cases intraosseous (io) infusion should be used as the method of choice. however, in practice, different problems are experienced with this procedure. to overcome the practical problems and to confirm the efficacy of io infusion in reversing hypovolemic shock, an animal model was used by emplo...

b ackground: animal models with various combination of host-parasite have long been employed to study malaria pathogenesis. here, we describe the combination of plasmodium berghei anka infec- tion in inbred icr mice as a model of cerebral malaria (cm). m ethods: infection in mice was initiated by intraperitoneal injection of 2 x 107  (0.2ml) parasitized red blood cells (prbcs). r esults: this m...

Two transfer factors have been prepared in an animal model system, the guinea pig. They are both small molecules, derived from the leukocytes of immunologically experienced individuals, and capable of transferring information for specific immune responses to naive individuals.

Although zoos are committed to wildlife conservation and have a long-term positive impact on visitors’ attitudes towards wildlife, the question of whether maintaining wild animals in human care is justified remains as animal welfare concerns grow understanding intelligence capacities broadens. Zoos always been subject debate, with conflicts between those who argue they save endangered species...

methanolic extract of solanum trilobatum linn. (mest) belonging to the family of solanacea was evaluated by hot plate and acetic acid induced writhing methods to assess its analgesic activity. the extract was also evaluated for its anti-inflammatory activity by subjecting into carrageenan, and cotton pellet induced granuloma tests for its effect on acute and chronic phase inflammation models in...

objective(s): adipose derived stem cells (adscs) can be engineered to express bone specific markers. the aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous adscs in alginate scaffold. materials and methods: in this study, 6 canine’s adscs were encapsulated in alginate and differentiated into osteoblasts. alkaline phosphatase assay (a...