A. In this paper, our aim is to incorporateGauss’s famous law in electrodynamics and some of Cauchy’s results in residue calculus within the general setting of deRham cohomology, that will be shown to provide amost natural environment for their development. Namely, it will be demonstrated that forms defined and closed on punctured spaces can be assigned a residue similar to the one defin...

Multidrug transporters form a large class of membrane proteins present in the cells of most organisms. These proteins bind to a variety of potentially cytotoxic compounds and remove them from the cell in an ATPor protondependent process (Zhelenova et al., 2000). Traditionally, multidrug transporters have been divided into four superfamilies: the ATP binding cassette (ABC) superfamily, the major...

Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic entity of unknown origin characterized by loss of inter-lobular bile ducts that was first described two decades ago. Although the diagnostic criteria have been described in detail, IAD continues to be a rare diagnosis. Our thorough literature search revealed less than a hundred cases of IAD reported. Here we present a 34-year-old fe...

Multidrug transporters form a large class of membrane proteins present in the cells of most organisms. These proteins bind to a variety of potentially cytotoxic compounds and remove them from the cell in an ATPor protondependent process (Zhelenova et al., 2000). Traditionally, multidrug transporters have been divided into four superfamilies: the ATP binding cassette (ABC) superfamily, the major...

Multidrug transporters form a large class of membrane proteins present in the cells of most organisms. These proteins bind to a variety of potentially cytotoxic compounds and remove them from the cell in an ATPor protondependent process (Zhelenova et al., 2000). Traditionally, multidrug transporters have been divided into four superfamilies: the ATP binding cassette (ABC) superfamily, the major...

Hippo throws its weight behind migrating cells L ucas et al. show that the Hippo pathway helps polarize actin so that groups of Drosophila cells can move in unison. Cells often journey in packs during development and cancer metastasis. In the Drosophila ovary, a group of 4–8 border cells traverses the egg chamber and sidles up to the maturing egg. This maneuver requires adjustments by the actin...

Machine learning concepts can find applications in many domains. We describe here one such application to the problem of fingerprint verification. In biometric verification using fingerprints, one often has to handle large archives of fingerprint images. When verifying an individual fingerprint, it is important to have a fast method at hand that selects suitable candidate images out of a large ...

f patience is a virtue, then Daniel Goodenough and Bruce Stevenson earned their wings in the pursuit of the first tight junction protein. Stevenson spent seven years as a graduate student with Goodenough (Harvard Medical School, Boston, MA) before the two worked out the conditions to purify fragile tight junction–enriched preparations from mouse liver (Stevenson and Goodenough, 1984). It was en...

This paper explores the role migration has played in development studies, and in debates on economic growth and poverty. It argues that, despite a recent surge of interest in international migration and remittances, research on human mobility particularly for labour within poor countries does not have the place it deserves, and that it used to have in the classical development literature. Revie...