نتایج جستجو برای: antiplatelet
تعداد نتایج: 10359 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE Antiplatelet therapy is currently one of the methods for preventing transient ischemic attacks and cerebral thrombosis. Because antiplatelet agents are generally administered on a long-term basis, patient compliance is an important factor. The purpose of this study was to determine the compliance of patients during antiplatelet therapy by testing platelet aggregation. M...
Satisfactory results have not yet been obtained in therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome (APS). We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with APS.The subjects were 20 ischemic stroke patients with antiphospholipid antib...
Optimal perioperative antiplatelet therapy in patients with coronary stents undergoing surgery still remains poorly defined and a matter of debate among cardiologists, surgeons and anaesthesiologists. Surgery represents one of the most common reasons for premature antiplatelet therapy discontinuation, which is associated with a significant increase in mortality and major adverse cardiac events,...
Platelet activation and aggregation play a central role in the patho physiology of thrombogenesis in ischemic heart disease. Dual antiplatelet therapy with aspirin and clopidogrel is currently the golden standard in the preven tion of cardiovascular complications after percutaneous coronary interven tion. Newer antiplatelet drugs are continuously marketed to respond to the limitations of clopid...
INTRODUCTION Cerebrovascular diseases are among the leading causes of death and disability in developed countries. Acetylsalicylic acid (ASA) and clopidogrel are the most widely-used antiplatelet drugs for secondary prevention of recurrent thromboembolic events. However, there have been cases in which antiplatelet drugs did not inhibit platelet activity; this phenomenon is called resistance, an...
How has the need to measure antiplatelet activity arisen? First, we do routinely measure hematologic or physiological surrogates for other effective secondary prevention strategies. Specifically, international normalized ratio monitoring is used to determine warfarin dosage; blood pressure is the yardstick for titration of antihypertensive agents and glycemic control using HbA1c in diabetes.1 I...
Antiplatelet drugs protect against myocardial infarction, stroke, cardiovascular death and other serious vascular events in patients with a history of previous vascular events or known risk factors for cardiovascular disease. Aspirin reduces the risk of serious vascular events in patients at high risk of such an event by about a quarter and is recommended as the first-line antiplatelet drug. Cl...
BACKGROUND Atherosclerotic peripheral arterial disease is associated with an increased risk of myocardial infarction, stroke, and death from cardiovascular causes. Antiplatelet drugs reduce this risk, but the role of oral anticoagulant agents in the prevention of cardiovascular complications in patients with peripheral arterial disease is unclear. METHODS We assigned patients with peripheral ...
BACKGROUND AND PURPOSE Lacunar stroke accounts for ≈25% of ischemic stroke, but optimal antiplatelet regimen to prevent stroke recurrence remains unclear. We aimed to evaluate the efficacy of antiplatelet agents in secondary stroke prevention after a lacunar stroke. METHODS We searched MEDLINE, Embase, and the Cochrane library for randomized controlled trials that reported risk of recurrent s...
OBJECTIVES/HYPOTHESIS Indications for antiplatelet and anticoagulation use are expanding. There is no evidence to direct therapeutic management in patients undergoing microlaryngeal surgeries. Our aim was to compare bleeding complications between microlaryngeal surgeries performed for patients preoperatively taken off and maintained on antiplatelet and/or anticoagulation therapy. STUDY DESIGN...
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