recent developments in medicine have given us a better insight into a group of disorders known as autoimmune diseases. in particular, advances have occurred in our understanding of the autoimmune inner ear disease (aied). in this article, the authors review the different postulated theories in the pathogenesis of this disease. the clinical presentation, the available para-clinical diagnostic to...

Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...

In 1970, Dixon penned an editorial, “What are sensitized cells doing in glomerulonephritis?”, a skeptical response to a paper showing that glomerulonephritis (GN) patients manifest not only humoral but also cellular responses to glomerular basement membrane (GBM) antigens (1, 2). The view that T cells represent important mediators of GN pathogenesis, rather than, at most, accompanying the suppo...

Dementia is defined as significant acquired cognitive impairment in one or more cognitive domains that represents a significant decline from previous baseline and interferes with independence in daily activities. Autoimmune dementia is a term that has been used to describe a steroid-responsive autoimmune disorder characterized by a rapidly progressive dementia with a fluctuating course. Even co...

pemphigoid gestationis (pg) is a rare autoimmune bullous dermatosis of pregnancy usually presents in the second or third trimester. it is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. pathogenesis of pg is not fully established, however, most patients develop circulating autoantibodies targeting the bullous pemphigoid (bp) 18...

the uterus and appendages was the direct result of gonorrhoea ; that the condition was very intractable to treatment; that it often remained latent for months or years before causing severe complications; that it led to subsequent sterility; and that where pregnancy did occur in association with it, the subsequent labour was often followed by sepsis. Following on the discovery of the gonococcus...

Ovarian and fallopian tube cytomegalovirus (CMV) infection is a rare finding, reported mostly in autopsy studies of immunocompromised patients. We report here a case of CMV salpingitis in a 22-year-old female, with Crohn's disease and on immunosuppressive drugs. The fallopian tube involvement by CMV infection was an incidental finding during resection of a large, matted mass involving the appen...