Background: An elevated level of cell-free DNA (cfDNA) in the blood circulation has detected in cancer patients in comparison with healthy controls. CfDNA circulation in plasma and serum extensively studied and the results are highly variable due to many factors influence the test results that was preanalytic factors as well as analytic factors. Objectives: Is there any difference in the concen...

Evaluation of: Gannon PO, Medelci S, Le Page C et al. Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis. Int. J. Cancer 128(10), 2326-2334 (2011). The frequency of two mutations (C282Y and D62H) of the hemochromatosis gene were investigated in women with ovarian cancer. A single allele mutation of the C282Y but not the H63D gene product was detected ...

OBJECTIVE To explore the predictive value of tumor markers, including cancer antigen 72-4 (CA72-4), cancer antigen 15-3 (CA15-3) and cancer antigen 125 (CA125), in single or combined detection, for the diagnosis of ovarian cancer. METHODS 120 patients diagnosed with ovarian cancer from August 2011 to March 2013 and 80 patients diagnosed with benign ovarian tumors were enrolled in this test, a...

BACKGROUND AND OBJECTIVE To explore whether reflectance spectroscopy can differentiate normal ovary, benign neoplasms, and ovarian cancer. STUDY DESIGN/MATERIALS AND METHODS Reflectance spectra (390-600 nm) were measured at three source-detector separations (SDS) in vivo at 64 sites in 16 patients undergoing oophorectomy. Parameters with largest statistical differences were identified. Based ...

Colorectal masses can be non-neoplasm, benign neoplasm and malignant neoplasm. Diagnosis of colorectal mass done by biopsy or surgery then followed histopathological examination. The aim this study was to described the histopathology feature in Anatomic Pathology Laboratory Arifin Achmad Regional Hospital Riau Province January 2015 - December 2019. This found 304 cases consisted men (55,6%) wom...

Primary ovarian leiomyoma is a rare benign tumour of the ovary, which is seen in women who are aged between 20 years to 65 years. Ovarian leiomyomas can be confused with other spindle cell tumours which display gross anatomical and histological similarities. A case of a primary leiomyoma of the ovary in a pre-menopausal female is being presented here, due to its huge size and unusual presentation.

[Introduction and Purpose] Schwannoma, also referred to as neurilemoma and neurinoma, is a benign nerve sheath tumor which usually occur in the soft tissues of the head and neck and extremities. When the tumors are located in deep structures such as the mediastinum and the retroperitoneum, those tend to be larger masses with degenerative changes as ancient (degenerated) schwannoma. Because schw...

Borderline ovarian tumors (BOT) were first described in 1929 by Taylor, which, due to the characteristics of the tumor, called it “semi malignant” or “borderline” [1]; subsequently, this group of tumors of the ovary were classified in 1973 by the World Health Organization as “low malignant potential ovarian tumor” [2] and, finally, in 2003 WHO separates them from carcinomas and call them border...

Mature cystic teratoma (MCT) is the most common type of ovarian germ cell tumor occurring in females of reproductive age. It is typically benign, but rare malignant transformations have been reported in 1-2% of the cases. Among a wide variety of malignancies arising in MCTs, high grade lymphomas are the least common. We present a case of a 45- years -old female with a unilateral adnexal ma...