Are benzodiazepines and anticonvulsants effective for patient with alcohol withdrawal symptoms？(Are anticonvulsants more effective than benzodiazepines？) P: alcohol withdrawal I: benzodiazepines and anticonvulsants C: placebo or active placebo O: prevent or relief alcohol symptoms (ex: delirium, seizure) , prevent re-intake alcohol 關鍵字(Key words): (alcohol withdrawal and benzodiazepine) (alcoho...

The undue use of benzodiazepines particularly among women has raised concern in the public health area. This qualitative study aimed at understanding the beliefs and values associated with undue use of benzodiazepines among women. Thirty-three participants (aged between 18 and 60) with a history of undue use of benzodiazepines in the past year were selected intentionally using specific criteria...

1,5-benzodiazepines are regarded as one of the most important classes of heterocyclic compounds as privileged structures and have vast range of applications in the field of medicine and chemistry. They are therefore attractive synthetic targets for organic and medicinal chemist. The current review article mainly covers the multicomponent green chemistry approaches for the synthesis of 1,5-benzo...

OBJECTIVE The purpose of the present preliminary study was to explore the prevalence of nonmedical abuse of benzodiazepines in a group of opiate-dependent patients who were on methadone maintenance treatment (MMT) program in outpatient clinics in the south-west of Tehran, Iran. METHODS 114 male and female opiate-dependent clients who met DSM.IV-TR criteria for opiate dependence with mean age ...

OBJECTIVE To systematically review the benefits and risks associated with the use of benzodiazepines to treat insomnia in adults. DATA SOURCES MEDLINE and the Cochrane Controlled Trials Registry were searched for English-language articles published from 1966 to December 1998 that described randomized controlled trials of benzodiazepines for the treatment of insomnia. Key words included "benzo...

OBJECTIVES Recently, more than 63% of the 52,404 drug overdose deaths in the United States involved heroin and opioid pain medications. More than 30% of opioid-related deaths also involved benzodiazepines. Previous studies examining the extent of concurrent opioid and benzodiazepine use have relied on prescription data. To gain fuller insight into the extent of the concurrent use problem, we an...

Benzodiazepines are useful and effective psychotropic agents used worldwide. However, the long term use of the drugs can lead to serious adverse health effects such as psychomotor and cognitive impairment, especially in the elderly. In Japan, there are very few reports concerning long-term use of benzodiazepines, and no countermeasures have been instituted. Thus, this study assessed the charact...

BACKGROUND Contrary to short-term use, long-term benzodiazepine use is undesirable. Nevertheless, its prevalence is high. To prevent long-term use, it is important to know which short-term users are at risk of becoming long-term users. OBJECTIVES The purpose of the present study was to identify patient-related factors of long-term versus short-term use of benzodiazepines. METHODS A cross-se...