CONTEXT Although bipolar disorder may have its onset during childhood, little is known about national trends in the diagnosis and management of bipolar disorder in young people. OBJECTIVES To present national trends in outpatient visits with a diagnosis of bipolar disorder and to compare the treatment provided to youth and adults during those visits. DESIGN We compare rates of growth betwee...

OBJECTIVES Bipolar disorder and schizophrenia share common pathophysiological processes and may have similar perceptual abnormalities. Mismatch negativity (MMN) and P3a - event-related potentials associated with auditory preattentional processing - have been extensively studied in schizophrenia, but rarely in bipolar disorder. Furthermore, MMN and P3a have not been examined between diagnostic s...

BACKGROUND Bipolar affective disorder may be associated with alterations in thyroid function. A comprehensive thyroid assessment is important for assessing clinical and sub-clinical imbalances linked to a variety of mood disorders like bipolar affective disorder. AIM To find out the association between bipolar affective disorder and thyroid dysfunction. MATERIALS AND METHOD The present cros...

BACKGROUND Bipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain. AIMS We sought to assess the impact of eQTL variants on bipolar disorder risk by combining data from both bipolar disorder genome-wide association studies (GWAS) and bra...

n contrast to the relationship between substance abuse and bipolar disorder, the relationship between bipolar I disorder and anxiety disorders is vastly underexplored, underappreciated, and certainly understudied. This inattention is surprising in light of the fact that anxiety disorders have the highest rate of comorbidity with bipolar disorder , exceeding the comorbidity rate even of substanc...

BACKGROUND Little is known about the impact of different types of stressful events (for example divorce v. bereavement) on unipolar depression compared with bipolar disorder. Inconsistencies exist concerning the association between independent events (beyond an individual's control, such as bereavement) and bipolar disorder. AIMS To examine the role of specific, independent and dependent even...

Bipolar disorder is one of the most debilitating and common illnesses worldwide. Individuals with bipolar disorder frequently present to clinical services when depressed but are often misdiagnosed with unipolar depression, leading to inadequate treatment and poor outcome. Increased accuracy in diagnosing bipolar disorder, especially during depression, is therefore a key long-term goal to improv...

BACKGROUND We investigated our translation of The Mood Disorder Questionnaire (MDQ) as a screening instrument for bipolar disorder in a psychiatric setting in Finland. METHODS In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and ...

background: there have been several studies conducted on the relationship between bipolar mood disorder and attention deficit hyperactivity disorder ( adhd) during the recent years, and in most of them the rate of this association had been estimated as 22-90% and had been reported as noticeable. the goal of this study is to determine the prevalence of adhd in patients with bipolar mood disorder...