We investigated the roles of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptor death receptor 5 (DR5) in the onset of acute leukemia and changes in their expression during chemotherapy. Bone marrow samples from 16 patients newly diagnosed with acute leukemia were collected before chemotherapy. Bone marrow samples from patients with non-hematologic malignancies ser...

OBJECTIVE Critical macromolecules such as DNA maybe damaged by free radicals that are generated from the interaction of ionizing radiation with biological systems. Melatonin and vitamin C have been shown to be direct free radical scavengers. The aim of this study was to investigate the in vivo/in vitro radioprotective effects of melatonin and vitamin C separately and combined against genotoxici...

Archival serum samples from elderly individuals with underlying chronic obstructive pulmonary disease (COPD) who were enrolled in a double-blind case-control study of seasonal influenza vaccine efficacy were assayed for cross-neutralizing antibody formation to avian influenza A (H5N1) virus. Of 118 serum samples, 58 were collected from influenza vaccinees (mean age 68.5 y), and 60 from placebo ...

five healthy adult male iranian donkeys (equus asinus) were selected and ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. before dosing, control blood samples were taken on day o. blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. the results showed that the activity of serumast and ldh increased on...

some evidence indicates that caffeine consumption before exercise may affect muscular damage. the aim of this study was to investigate the effects of caffeine consumption (6mg/kg) following a session of resistance exercise on creatine kinase (ck) and lactate dehydrogenase (ldh) in active men. 20 male physical education students (age 21.22±1.25 years, height 175.13±6.88 cm, weight 69.22±7.10 kg ...

b ackground: in this study the concentration of lysozyme in blood plasma of  microtus agrestis, clethrinomys glareolus , apodemus sylvaticus, bk rats and outbred white mice before and after infection with culture forms of trypanosoma microti, t, evotomys, t. grosi, t. lewisi and t. musculi respectively was measured. m ethods: blood samples of rodents, microtus agrestis, clethrionomys glareolus,...

The aims of this study were to assess the effect of transarterial chemoembolization (TACE) on circulating tumor cells (CTCs) in the peripheral blood and right atrium of patients with HCC and to evaluate whether perioperative shedding of CTCs affects time to progression of HCC. Before and after TACE, peripheral and right atrial blood samples (7.5 mL) were collected from 42 patients with HCC. CTC...

babesiosis is an important tickborne disease in the sheep of iran. objectives: a molecular study was carried out in north khorasan province, iran in 2010-2011, designed to identify babesia spp. infection of both sheep and ticks. methods: ninety sheep from different flocks were clinically examined and blood samples were collected with ixodid  ticks . the collected ticks were separated into 82 ti...