breast cancer is common and is considered second cause of cancer related mortality in females. regarding importance of breast cancer, more investigation in this field is recommended. for many years investigators believed that neoplasms were not innervated but new findings have proved otherwise. this descriptive study was carried out to compare number of nerve fibers in benign, malignant and nor...

background: mammary paget’s disease is an uncommon form of primary breast cancer. the aim of this study is to assess our institution’s experience in its management. methods: we retrospectively reviewed the medical records of 53 female patients with histologically confirmed paget’s disease, treated at the salah azaïz institute between 2001 and 2010. results: there were palpable masses in 71.7% o...

There have been some reports of coincidental presentation of breast carcinoma and phyllodes tumor in the same breast. Most of the cases were carcinoma that arose from a phyllodes tumor with a histologically identified transitional area, and they behaved less aggressively than the usually encountered carcinoma. Collision tumors are rare clinical entities in which two histologically distinct tumo...

Cytomegalovirus (CMV) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. It is supposed that CMV is a risk factor for breast cancer. The aim of this study was to determine the frequency of CMV among benign and malignant breast tumors. Paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from Toos and Firoozgar...

Gastrointestinal (GI) metastases from primary breast carcinoma are rare but more common in invasive lobular carcinoma than invasive ductal carcinoma. The symptoms may be non-specific and the presentation can occur many years after the initial primary breast carcinoma. Radiological and endoscopic findings can be difficult to distinguish from inflammatory bowel disease and primary carcinoma of th...

Metaplastic breast carcinoma accounts for less than 1% of breast malignancies. Huvos et al. first introduced the term metaplastic carcinoma in 1974. It is usually seen together with poorly differentiated ductal carcinoma of the breast. Within its mesenchymal components, undifferentiated connective tissue cells, fibroblasts, osteoblasts and chondroblasts can be found. Metaplastic breast carcinom...

BACKGROUND Historically, female breast carcinoma has been viewed as an etiologically homogeneous disease associated with rapidly increasing incidence rates until age 50 years, followed by a slower rate of increase among older women. More recent studies, however, have shown distinct age incidence patterns for female breast cancer when stratified by estrogen receptor (ER) expression and/or histop...

Glycogen rich Clear cell carcinoma of the breast is a rare subtype of breast carcinoma occurring in 1.4 to 2.7 % of breast carcinoma patients. The significance of understanding this carcinoma lies in the fact that they usually have an aggressive course and an adverse prognosis. Here we present a case of 50 yearsold female with a left sided breast lump for 2 yearswhich histologically showed the ...