To examine effects of body size change on postmenopausal breast cancer, the authors conducted a population-based case-control study among 990 cases and 1,006 controls participating in the Long Island Breast Cancer Study Project in 1996-1997. Women who had gained more than 15 kg (33 pounds) since age 20 years were at a 1.6-fold increased risk of breast cancer (95% confidence interval (CI): 1.11,...

M aintaining a healthy weight and exercising regularly have become standard advice for lowering the risk of breast cancer. But researchers are finding that these lifestyle changes may also be associated with better survival and lower recurrence in women with breast cancer. New evidence from several fronts suggests that excess body fat promotes breast cancer growth and that reducing body fat and...

PURPOSE/OBJECTIVES To examine the research literature regarding the effects of exercise on body weight and composition in breast cancer survivors. DATA SOURCES Primary studies in English published from 1989-2004, located through electronic databases, hand searches, and personal contacts. DATA SYNTHESIS Of 1,314 studies screened, 14 met all inclusion criteria. Body weight and composition gen...

Five single nucleotide polymorphisms (SNP) of the chicken insulin-like factor binding protein 2 (IGFBP2) gene were selected to genotype a F2 designed population with restriction fragment length polymorphisms and single stranded-conformation polymorphisms. The associations of the SNP and their haplotypes with chicken growth and carcass traits were analyzed. Results showed that the difference ind...

PURPOSE Weight gain often occurs after breast cancer diagnosis and significantly impacts the general health of cancer survivors. While the number of breast cancer survivors is increasing, few studies have reported data on weight change beyond 5 years post-diagnosis. We investigated weight change and associated factors in long-term survivors of breast cancer. PATIENTS AND METHODS Medical recor...

Despite extensive research on obesity and breast cancer in recent decades, inconsistencies in the literature exist. The authors examined prospectively the relation between adult relative weight (weight (kg)/height (m)1.5) and breast cancer risk in a cohort of 54,896 women aged 31-89 years who had previously participated in the Breast Cancer Detection Demonstration Project. During a mean follow-...

phyllodes tumors account for less than 1% of breast tumors in women. giant phyllodes tumors are larger than 10 cm in diameter. a 40-year-old lady presented with a left breast lump that was present for two years. she underwent a simple mastectomy. the tumor was 30×26×21 cm in size, weighed 15 kg and had a density of 0.915 gr/cm3. we believe this patient had the third largest breast phyllodes tum...