BACKGROUND Hypercortisolemia has been suggested as a primary hormonal mediator of whole-body catabolism following severe burn injury. Ketoconazole, an anti-fungal agent, inhibits cortisol synthesis. We, therefore, studied the effect of ketoconazole on post-burn cortisol levels and the hyper-catabolic response in a prospective randomized trial (block randomization 2:1). METHODOLOGY/PRINCIPAL F...

Discontinuous permafrost in the North American boreal forest is strongly influenced by the effects of ecological succession on the accumulation of surface organic matter, making permafrost vulnerable to degradation resulting from fire disturbance. To assess factors affecting permafrost degradation after wildfire, we compared vegetation composition and soil properties between recently burned and...

Biomass burning is a global phenomenon and systematic burned area mapping is of increasing importance for science and applications. With high spatial resolution and novelty in band design, the recently launched Sentinel-2A satellite provides a new opportunity for moderate spatial resolution burned area mapping. This study examines the performance of the Sentinel-2A Multi Spectral Instrument (MS...

Introduction Nosocomial pneumonia is a major source of morbidity and mortality after severe burns. Burned patients suffer trace element deficiencies and depressed antioxidant and immune defences. This study aimed at determining the effect of trace element supplementation on nosocomial or intensive care unit (ICU)-acquired pneumonia. Methods Two consecutive, randomised, double-blinded, supplemen...

We report on the numerical separation of burned and unburned vegetation classes using diVerent bi-spectral spaces, based on the analysis of spectro-radiometric data collected in situ and convolved to ve spectral bands at red to mid-infrared (MIR) wavelengths. A combination of two MIR bands was found to have strong spectral separation of burned and unburned samples. Using these bands, a spectral...

Burned landscapes present several challenges to quantifying landscape carbon balance. Fire scars are composed of a mosaic of patches that differ in burn severity, which may influence postfire carbon budgets through damage to vegetation and carbon stocks. We deployed three eddy covariance towers along a burn severity gradient (i.e., severely burned, moderately burned, and unburned tundra) to mon...

BACKGROUND Burned patients are usually resistant to the neuromuscular effects of nondepolarizing relaxants, mostly because of receptor changes. The magnitude of the resistance is related to burn size and time after burn. Mivacurium is a muscle relaxant, degraded by plasma cholinesterase, whose enzyme activity is decreased in burns. The present study tested the hypothesis that burn-induced depre...

BACKGROUND Burn injury may be associated with long-term rehabilitation and disability, while research studies on the functional performance after injuries, quality of life (QOL), and abilities to return to work of burn patients are limited. These outcomes are related not just to the degree and nature of injuries, but also to the socio-economical background of the society. This study aimed to id...

BACKGROUND The aim of this study is to perform a retrospective analysis of the causes of burns observed in children in the eastern provinces of Turkey. METHOD In this study, patients were studied retrospectively with regard to their age, sex, cause of burns, seasonal variations, social and economic factors, length of hospital stay, burned body surface area, medical history, site of injury, an...