male breast cancer is a rare disease with an increasing trend. due to limited information especially about the genetic basis of the disease in iran and the lower age of its onset, the disease requires more attention. the aim of this study was to screen the male patients with breast cancer for brca mutations as well as tissue markers of estrogen receptor (er), progesterone receptor (pr), human e...

Early detection is the most important strategy for controlling and management of cancer, which can significantly increase survival rate by detecting disease in early stages rapid treating preventing progression disease. Based on existence specific cell frequencies form response each to its own frequency difference between normal tumor levels as a hallmark cancer detection, we suggest using Grap...

Colon carcinoma is a rare disease in the pediatric population. Here is a report on a 17-year-old male adolescent with colon adenocarcinoma who presented with recurrent epigastric colic pain for 1 month. Diagnostic laparoscopic surgery revealed a 3.2 3 cm tumor at the ascending colon, with serosal involvement and peritoneal metastasis. Clinical differences of colorectal carcinoma among children ...

Cancer is a disease caused by mutation during normal growth generating cells that escape the cellular control processes that normally keep growth in check. The human genome comprises 3 billion paired bases (the 4 letters, A, T, G, C of DNA), which needs to be duplicated at each cell division. Duplication is not 100% accurate and has a small error rate for inserting the wrong base of about 1 err...

To cite: Saba R, Ali AM, Kwatra SG, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2012008344 DESCRIPTION A 35-year-old male with a history of rheumatoid arthritis and rheumatoid pulmonary nodules and Graves’ disease was admitted to the hospital due to new onset fever, worsening dyspnoea and cough. Laboratory workup showed leukocytosis, haematuria, elevate...

Background CheckPoint Inhibitors (CPI) Induced arthritis (IA) is an immune related adverse event (irAEs) occurring in 0.5 to 2% of CPI-treated patients between 3 weeks up 24 months after initiation therapy. IA usually described as a seronegative oligoarticular inflammatory joint disease but has been for long underdiagnosed and inappropriately evaluated. Objectives To evaluate the added value sy...

background: breast cancer (bc) is the second most commonly diagnosed cancer after lung cancer. survival of bc patients is affected by intermediate events. this study was aimed to investigate the disease course of primary non-metastatic bc patients with first recurrence of the tumor (frt) as the intermediate event using the illness- death model. methods: this retrospective cohort study was condu...

introduction:the external beam radiation therapy for patients with left breast cancer at the mastectomy site may cause myocardial perfusion abnormalities. we intended to study the change of these abnormalities at short and long term post radiotherapy follow up. methods: twenty patients with left and 20 patients with right breast cancer comprised the exposed and control groups, respectively. the...