UNLABELLED This study was aimed to comparison of the effects of the chronic use of the Ribavirin and caffeic acid phenethyl ester (CAPE) on the pancreatic damage and hepatotoxicity in rats. METHODS The rats were given orally 30 mg/kg/day doses of Ribavirin for 30 days, and intraperitoneally 10 μmol/kg doses of CAPE. The 37 rats were divided into 4 groups: (I) Control (n=7), (II) Ribavirin (R)...

BACKGROUND/AIM In this study, the in vitro and in vivo effectiveness of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE) in combination with bortezomib, a proteasome inhibitor, was explored in multiple myeloma (MM) cells. MATERIALS AND METHODS The cytotoxic effects of CAPE and bortezomib were determined by XTT cell proliferation assay. Apoptosis levels were analyzed with annex...

Nigel Lowther Love is associate professor of linguistics at University of Cape Town. He was born in 1950 in the U.K. He received his B.A. (1973), M.A. (1976) and D. Phil. (1976) from Oxford University. His Ph.D. thesis title was: The generative phonological analysis of non-vocalic alternations in Modern French. Nigel Love has been the invited lecturer or conference speaker at universities in: A...

Intense thunderstorms produce rapid cloud updrafts and may be associated with a range of destructive weather events. An important ingredient in measures of the potential for intense thunderstorms is the convective available potential energy (CAPE). Climate models project increases in summertime mean CAPE in the tropics and subtropics in response to global warming, but the physical mechanisms re...

Grant Theron, Anil Pooran, Jonny Peter, Richard van Zyl-Smit, Hridesh Kumar Mishra, Richard Meldau, Greg Calligaro, Brian Allwood, Surendra Kumar Sharma, Rod Dawson, Keertan Dheda 3* Lung Infection and Immunity Unit, Division of Pulmonology & UCT Lung Institute, Department of Medicine, University of Cape Town, Cape Town, South Africa. Department of Medicine, All India Institute of Medical Scien...

Located on the northwest coast of Ross Island in McMurdo Sound, Cape Bird features virtually unweathered surface drift with erratics from the Transantarctic Mountains (TAM) and with enclosed marine shell fragments. This Cape Bird drift is cut by Holocene beaches. The chronology of drift deposition and beach formation comes from AMS radiocarbon dates of associated marine shells, and of penguin b...

We prove a Noether’s theorem for fractional variational problems with Riesz-Caputo derivatives. Both Lagrangian and Hamiltonian formulations are obtained. Illustrative examples in the fractional context of the calculus of variations and optimal control are given.

1 Department of Computer Science, Faculty of Science, University of Cape Town, Private Bag X3, Rondebosch, Cape Town 7701, South Africa 2 School of Computing, College of Science, Engineering and Technology, University of South Africa (UNISA), P.O. Box 392, Pretoria 0003, South Africa 3 Department of Computer Science, Faculty of Science, University of Western Cape, Private Bag X17, Bellville 753...

Division of Epidemiology & Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Anzio Road, Observatory 7925 Cape Town, South Africa Centre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, South Africa ICAP, Columbia University Mailman School of Public Health, 10032 NY, USA *Author for corresponden...