نتایج جستجو برای: cd62p
تعداد نتایج: 295 فیلتر نتایج به سال:
BACKGROUND Dual anti-platelet therapy with aspirin and a thienopyridine (DAT) is used to prevent stent thrombosis after percutaneous coronary intervention (PCI). Low response to clopidogrel therapy (LR) occurs, but laboratory tests have a controversial role in the identification of this condition. METHODS We studied LR in patients with stable angina undergoing elective PCI, all on DAT for at ...
P-selectin (CD62P), an adhesion molecule localized in platelet alpha-granules and endothelial cell Weibel-Palade bodies, is rapidly expressed on the surface of activated cells. This adhesion molecule, a member of the selectin family, mediates leucocyte interactions with activated platelets or endothelial cells. The aim of this study was to identify and characterize the epitope of a functional b...
BACKGROUND Buffy-coat processing allows for the use of platelet additive solutions (PASs). PASs reduce plasma-associated transfusion reactions and conserve plasma for transfusion or fractionation. Platelet (PLT) storage in plasma was compared to storage in three commercially available PASs compared to assess their influence on in vitro laboratory variables. STUDY DESIGN AND METHODS Platelet c...
Objectives To compare the clinical effects of intravenously and orally administered aspirin in the treatment for acute coronary syndrome (ACS), and to evaluate the adverse effects of intravenous administration of aspirin. Methods One hundred and twentyfive patients with unstable angina pectoris or acute myocardial infarction were randomized into three groups: group 1 received intravenous aspiri...
BACKGROUND This study was performed to analyze the influence of either aspirin, ticlopidine, or their combination on platelet activation and aggregation parameters after stent implantation. METHODS AND RESULTS Sixty-one patients with successful implantation of a single Palmaz-Schatz stent in a native coronary artery were randomly assigned to either group A (aspirin 300 mg/d+ticlopidine 2X250 ...
سابقه و هدف: در جریان حمل و نقل و در بیمارستانها تداوم آژیتاسیون و دمای نگهداری(24-20 درجه سانتیگراد) واحدهای پلاکت به هم میخورد .هدف از این مطالعه ارزیابی کیفی واحدهای پلاکتی تولید شده در پایگاه انتقال خون تهران بعد از توقف آژیتاسیون به مدت 6 ساعت در دمای 24-20 سانتیگراد بود که برای اولین بار در ایران انجام گرفت. روش بررسی: در این مطالعه مقطعی، 20 واحد پلاکت به دست آمده از pooled پلاکتی...
BACKGROUND Cell-surface adhesion molecules regulate multiple intercellular and intracellular processes and play important roles in inflammation by facilitating leukocyte endothelial transmigration. Whether cardiomyocytes express surface-adhesion molecules related to inflammation and the effect of pro-inflammatory mediators remain unknown. MATERIALS AND METHODS In the present study, the expres...
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