OF THE DISSERTATION Identification of Novel Fluid Biomarkers for Alzheimer’s Disease by Rebecca June Craig-Schapiro Doctor of Philosophy in Biology and Biomedical Sciences Neurosciences Program Washington University in St. Louis, 2012 Dr. David M. Holtzman, Chairperson Clinicopathological studies suggest that Alzheimer’s disease (AD) pathology begins to appear ~10-20 years before the resulting ...

BACKGROUND/AIMS Measuring and predicting Alzheimer's disease (AD) progression is important in order to adjust treatment and allocate care resources. We aimed to identify a combination of subtests from the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Battery (CERAD-NB) that best correlated with AD progression in follow-up as well as to predict AD progression. M...

The effect of doses of mixed gamma-neutron radiations or 14 MeV neutrons on the urinary excretion of deoxycytidine (CdR) was evaluated as a biodosimeter in rats. The rats were exposed to doses in the range from 22 to 780 rads. The excretion of CdR in the urine of irradiated rats during the 4to 12-hour postirradiation interval was a function of dose over the range of 22 to 376 radsThis response ...

BACKGROUND/AIMS Studying the gut microbiota in unaffected relatives of people with Crohn's disease (CD) may advance our understanding of the role of bacteria in disease aetiology. METHODS Faecal microbiota composition (16S rRNA gene sequencing), genetic functional capacity (shotgun metagenomics) and faecal short chain fatty acids (SCFA) were compared in unaffected adult relatives of CD childr...

BACKGROUND In vivo hepatic phosphorus-31 magnetic resonance spectroscopy (MRS) provides non-invasive information about phospholipid metabolism. AIMS To delineate MRS abnormalities in patients with chronic ductopenic rejection (CDR) and to characterise spectral changes by in vitro MRS and electron microscopy. PATIENTS AND METHODS Sixteen liver transplant recipients (four with CDR; 12 with go...

THE ASSESSMENT OF PATIENTS' PERCEPTION AND SATISFACTION OF RADIOLOGY WAITING TIME IN UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL. 1 1 2 1 1 2 1 Nwobi IC, Luntsi G, Ahmadu MS, Nkubli FB, Kawu HD, Dauda F, Moi AS, 1 3 Abubakar GM, Tahir MB 1 Department of Medical Radiography College of Medical Sciences, University of Maiduguri, 2 Borno State, Radiology Department University of Maiduguri Teaching Ho...

integral process. Research article acts as a platform for the dissemination of knowledge on various research carried out in the scientific world. Further, it creates a pathway to many researchers to carry out research work. Of the many reasons of publication of a research work, some of them are particularly based on the promotion of the researcher and other academic benefits. Post-publication, ...

A method for regenerating pigeonpea {Cajanus cajan (L.) Millsp.} plants has been developed using cotyledonary nods and embroyonic axes of mature seeds as explants. A large number of shoot buds were induced directly from explants of genotypes Pusa-9 and Bahar when cultured on different basal media fortified with a range of BAP concentrations (0–2 mg/l) and 0–0.5 mg/l gibberellic acid (GA ) eithe...

This research was aimed to study the etiology of optic atrophy and comparison of optic disc morphology between compressive and glaucomatous optic atrophy. It included 72 cases of optic atrophy admitted in Maharani Laxmi Bai Medical College, Jhansi between January 2016 to May 2017. Assessment of present complaints, examination of the eyes, visual acuity, refraction, perimetry, Optical Coherence ...

In an attempt to understand the pathology of E.coli mastitis, six lactating rabbits each were infected with E. coli strains O9(36) and O147 isolated from bovine mastitis cases. One rabbit was euthanized at 24 hrs interval and the mammary glands were analyzed by gross and histopathology, electron microscopy and immunohistochemistry for induction of mastitis. The infected rabbits grossly revealed...