This study describes development of a novel controlled drug release system for multiple drugs, it consisted of Chitosan nanoparticles/PCL composite electrospun nanofibers with core-sheath structures. Two model agents' rhodamine B and naproxen were successfully loaded in the core and sheath region respectively. The behavior of these two agents demonstrated a good controlled release and temporali...

The native extracellular matrix (ECM) is composed of a cross-linked porous network of multifibril collagens and glycosaminoglycans. Nanofibrous scaffolds of silk fibroin (SF) and hydroxybutyl chitosan (HBC) blends were fabricated using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) and trifluoroacetic acid (TFA) as solvents to biomimic the native ECM via electrospinning. Scanning electronic microscop...

Objective(s): The present study aimed to fabricate chitosan/polyethylene oxide (CS/PEO) electrospun nanofibers loaded with Aloe vera extract for biomedical applications. The polymer-to-extract ratio and electrospinning parameters (applied voltage and nozzle-to-collector distance) were evaluated in order to optimize the process of nanofiber fabrication. Materials and Methods: The character...

Nanofibers mats of chitosan (CTS)/polyvinyl alcohol (PVA)/halloysite nanoclay and drug loaded CTS/PVA/halloysite nanoclay//3-glycidyoxypropyl trimethoxysilane were fabricated using the electrospinning method. Electrospun nanofiber samples characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA). FTIR confirmed chemical...