A 4-year-old female French bulldog presented with a 6-month history of right-sided head tilt and acute onset ataxia. Magnetic resonance imaging (MRI) showed a large mass lesion at the cerebellomedullary pontine angle. The dog was able to stand and walk after beginning symptomatic therapy with prednisolone, acetazolamide and glycerin. Magnetic resonance imaging 10 months after the first examinat...

children but rare in adults. In addition, the disease categories encountered differ according to the patient’s age; in adults, the most common fourth ventricular neoplasm is metastasis (1). The most frequent primary intraventricular tumor of the posterior fossa is the ependymoma; other tumors include choroid plexus papillomas and an occasional meningioma (2). Subependymomas can occur in the inf...

A rare case of extensively disseminating multiple benign choroid plexus papilloma is shown. The patient first reported with high-grade hydrocephalus and two tumours in the 3rd and 4th ventricle was treated by atrioventricular shunt insertion, subtotal resection of the 4th ventricle tumour, and adjuvant 60Co irradiation of the posterior fossa. The dissemination that followed was revealed by comp...

BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...