OBJECTIVES To develop an "overlap syndrome (OS)" rat model by intermittent hypoxia (IH) exposure on the base of pre-existing emphysema, and to explore whether "OS" exposure results in more severe systemic inflammation, and whether the inflammation changes levels of coagulant/anticoagulant factors and oxidative stress status. METHODS Sixty Wistar rats were put into 4 groups: Control group; IH ...

The traditional coagulant assay for plasma factor XI suffers from a relatively high coefficient of variation, the need for rare congenitally deficient plasma, and a poor correlation between precision and sensitivity. We have developed a simple functional amidolytic assay for factor XI in plasma using the chromogenic substrate PyrGlu-Pro-Arg-p-nitroanilide (S-2366). After inactivation of alpha 1...

The need to ameliorate some of the inherent limitations in the use of alum in water purification engendered these studies. Synthetic water of varying turbidities (50, 100, 300 NTU) and varying pHs (2, 3, and 4), but low alkalinity were prepared. The results from the different studies showed that water of lower residual turbidity could be got from the use of 50% of optimum alum dose when combine...

Ticks are blood-feeding arthropods widely distributed in the world and vectors of several diseases. As haematophagy demands evasion strategies and repeatedly infested hosts develop protective immune responses, we investigated the mechanisms of the Rhipicephalus (Boophilus) microplus saliva anti-haemostatic activity and the possible relationship between the acquired natural anti-tick host resist...

Twenty-six patients with hereditary factor VII deficiency (VII:C less than 10%) were evaluated using a panel of three thromboplastins of varying species and tissue origin in both coagulant and chromogenic assay systems. Normal values for the coagulation and chromogenic assays were 104% +/- 7% and 108% +/- 21%, respectively. Factor VII antigen was measured by a specific radioimmunoassay (normal,...

BACKGROUND Strenuous exercise may trigger myocardial infarction through increased pro-coagulant activity. We aimed to investigate whether patients referred for exercise testing, who were found to have angiographically verified coronary artery disease (CAD), have a more hypercoagulable profile during exercise testing than those without CAD. METHODS Patients with symptoms of stable CAD were exa...

Issam Najm, Carol Tate, and Douglas Selby he upcoming Disinfectants/Disinfection ByProducts (D/DBP) Rule recognizes that a greater reduction in the total organic carbon (TOC) concentration of a natural water supply may appreciably reduce the concentrations of known and unknown DBPs formed during chlorination. Thus, the D/DBP Rule requires that conventional surface water treatment plants use enh...

In this study arsenate [As(V)] removal from drinking water by coagulation process was investigated. Ferric chloride (FeCl3.6H2O) and ferrous sulfate (FeSO4.7H2O) were used as coagulant. The effects of major operating variables such as coagulant dose (1–30 mg/L) and pH (5.5–9.5) were investigated. Ferric chloride and ferrous sulfate were found as effective and reliable coagulant due to required ...

Ras cheeses were manufactured using aqueous extract of globe artichoke or artichoke flowers (Cynara scolymus) proteinase as coagulant were compared to calf rennet. There were slight differences between chemical composition of cheese made using vegetable coagulants or calf rennet. Cheeses manufactured with artichoke extract as coagulant exhibited higher (p < 0.05) levels of water soluble nitroge...