The prevalence of mitral valve prolapse was investigated in 126 patients with hyperthyroidism due to Graves' disease or toxic nodular goitre and that of hyperthyroidism in 64 patients with mitral valve prolapse. One hundred and eleven asymptomatic healthy subjects comprised a control group. The patients with hyperthyroidism were divided into those with Graves' disease and those with toxic nodul...

OBJECTIVE Epidermal growth factor (EGF) is believed to be one of the most potent growth factors for the thyroid gland. DESIGN AND METHODS We tested plasma EGF concentrations (radioreceptor method) in patients with non-toxic nodular goitre (NNG). Blood samples from patients with NNG were collected on the day before the surgery, during subtotal thyroidectomy (sTx)--from peripheral and thyroid v...

OBJECTIVE To assess the diagnostic value of dynamic contrast medium-enhanced magnetic resonance imaging (DCE-MRI) in detection of thyroid carcinoma compared with fine-needle aspiration biopsy and frozen section analysis in multinodular goiter. DESIGN Prospective clinical study. SETTING University hospital. PATIENTS Thirty consecutive patients with nodular goiter without any clinical risk ...

377 patients with single thyroid nodule who clinically were candidates for surgery, were selected from the patients that referred to the clinics of endocrinology at Namazee Hospital, Shiraz Medical School. Fine needle aspiration (FNA) was carried out without performing thyroid scan and the results were compared with histology obtained by surgery to establish its accuracy in our center. whic...

In 1965 Werner and Spooner described a test of thyroid autonomy which has found wide acceptance in medical practice (1). They found that administra tion of l-triiodothyronine (T-3) in doses of 75 to 150 mcg daily, for seven days, suppressed the thyroid uptake of 131!in normal persons and in most patients with nontoxic goiter. Little or no change occurred in patients with diffuse toxic goiter (G...

from cancer of the alimentary tract eventually occurred. In collecting data for a book on iodine and the incidence of goiter (1) the accompanying maps were obtained, showing a resemblance between the distribution of nodular goiter (Fig. 1) and cancer in Switzerland (Fig. 2) . The relation between goiter and cancer was mentioned by Bayard and Hunziker and studied statistically by Stiner (2). De ...

The aim of the present study was to determine associations of thyroid hormone levels and different metabolic parameters and anthropometric measurements with volume of nodular and nonnodular thyroid as well as with prevalence of goiter and thyroid nodules in middle-aged euthyroid subjects. Methods. The study consisted of 317 euthyroid subjects aged 48-49 from the Kaunas Cardiovascular Risk Cohor...

OBJECTIVE The aim of this study is to investigate the presence of pyramidal lobe in thyroid scintigraphy and to compare the presence of pyramidal lobe in different thyroid pathologies between genders. METHODS Images of 866 patients (663 female, 203 male) with ages ranging from 8 to 85 were evaluated retrospectively. Presence of pyramidal lobe and its location were established in images. Patie...

The D727E germline polymorphism in the thyroid-stimulating hormone receptor gene (TSHR) may cause genetic susceptibility to the development of goiter. Therefore, in this study we investigated allele frequencies and genotype distributions of the TSHR D727E polymorphism, their association with clinical parameters, and the development of goiter in the Turkish population. We investigated the TSHR D...

We describe two different cases of prinary thyroid lymphoma (PTL). PTL is a rare malignancy. Nevertheless, it frequently presents diagnostic and therapeutic challenges. The first patient, a 79-year-old female, presented with a large, painless thyroid mass accompanied by severe obstructive symptoms of the upper respiratory and gastrointestinal track. The second patient (67-year-old female) prese...