aim : the aim of this study was to evaluate the mortality rates and trends from gastrointestinal (gi) cancer in iranian population from 1995 to 2003. background : cancer is the third most common cause of death in iran. gastrointestinal cancer is the most important causes of mortality due to cancer. the cancer mortality data is important to monitor the effects of screening program, earlier diagn...

Background: Colorectal cancer (CRC) is one of the lethal cancers all over world. Early detection colorectal has been shown to reduce incidence and mortality. Primary care physicians have a crucial role in early cancer. This study aims explore knowledge, attitude practice primary Bahrain towards CRC screening determine barriers related screening. Methods: A cross sectional was carried out among ...

aim : this study investigated the role of cd86 +237 g/c polymorphism in intensifying the risk of crc development. background : colorectal cancer (crc) is a multi-factorial diseases. genetic background could affect the susceptibility of individuals to crc development. cd86 is a co-stimulatory factor on antigen-presenting cells that plays key roles in several cancer related mechanisms such as aut...

Background While colorectal cancer (CRC) is one of the most preventable causes of cancer mortality, it is one of the leading causes of cancer death in Canada where CRC screening uptake is suboptimal. Given the increased rate of mortality and morbidity among mental health patients, their condition could be a potential barrier to CRC screening due to greater difficulties in adhering to behaviours...

Introduction Colorectal carcinomas (CRC) are one of the leading causes of cancer deaths, but their clinicopathological characteristics are not well documented in Turkish population. We retrospectively analyzed 535 resection specimens of patients diagnosed with primary CRC between the years of 2000-2007, to refine the pathological criteria for the routine analyses of colorectal cancer specimens....

BACKGROUND AND AIMS Although adenomas may be precursors to colorectal cancers (CRC), knowledge concerning the development of metachronous CRC is scarce. We assessed whether differential expression of cell-cycle and apoptosis-regulating proteins and a monotonous population of elongated cells (MPECs) in colorectal adenomas could predict metachronous CRC. METHODS Application of immunohistochemis...

Background and Purpose: Colorectal cancer (CRC) is one of the most highly prevalent and life-threatening digestive tract cancers. CRC and its treatment are associated with numerous complications in the patients. Orem’s self-care model is a theory on clinical improvement and reducing fatigue in patients with CRC. This study aimed to investigate the effects of Orem’s self-care theor...

The emergence of chemoresistance is a major limitation of colorectal cancer (CRC) therapies and novel biologically based therapies are urgently needed. Natural products represent a novel potential anticancer therapy. Gambogic acid (GA), a small molecule derived from Garcinia hanburyi Hook. f., has been demonstrated to be highly cytotoxic to several types of cancer cells and have low toxicity to...

BACKGROUND Patients with hereditary non-poliposys colorectal cancer (HNPCC) have better prognosis than sporadic colorectal cancer (CRC). Aim of our retrospective study was to compare the overall survival between sporadic CRC and HNPCC patients. METHODS We analyzed a cohort of 40 (25 males and 15 females) HNPCC cases with a hospital consecutive series of 573 (312 males and 261 females) sporadi...