نتایج جستجو برای: conformational changes

تعداد نتایج: 897581  

Journal: :Structure 2004
Ying Zhang Wei Zhang Steven Ogata David Clements James H Strauss Timothy S Baker Richard J Kuhn Michael G Rossmann

Dengue virus, a member of the Flaviviridae family, has a surface composed of 180 copies each of the envelope (E) glycoprotein and the membrane (M) protein. The crystal structure of an N-terminal fragment of E has been determined and compared with a previously described structure. The primary difference between these structures is a 10 degrees rotation about a hinge relating the fusion domain DI...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1971
M H Schreier H Noll

In a purified system containing poly(U) and ribosomal subunits from Escherichia coli, and purified transfer factors T and G, the active ribosomal complex passes through a cycle of contraction and expansion with the addition of each amino acid; aminoacyl-tRNA binding catalyzed by T produces the stable compact state, corresponding to the 70S conformation, whereas translocation with G expands the ...

Journal: :Biochemistry 2007
Shao-Chun Wang C Ted Lee

The interaction of a light-responsive surfactant with lysozyme at pH 5.0 has been investigated as a means to control protein structure and enzymatic activity with light illumination. The cationic azobenzene surfactant undergoes a reversible photoisomerization upon exposure to the appropriate wavelength of light, with the visible-light (trans) form being more hydrophobic and, thus, inducing a gr...

Journal: :The Journal of chemical physics 2005
Thomas F Miller David C Clary Anthony J H M Meijer

We present quantum dynamical calculations on the conformational changes of glycine in collisions with the He, Ne, and Ar rare-gas atoms. For two conformer interconversion processes (III-->I and IV-->I), we find that the probability of interconversion is dependent on several factors, including the energy of the collision, the angle at which the colliding atom approaches the glycine molecule, and...

2017
Elizabeth A. Allegretto

Introduction Protease Digestion Experiments ER Crystal Structures Peptide Phage Display Technology References

Journal: :Circulation research 1969
S Bloom P A Cancilla

Journal: :Biopolymers 2005
Nicolas Taulier Irina V Beletskaya Tigran V Chalikian

We used high-precision density and ultrasonic velocity measurements to characterize the native (N), molten globule (MG), and unfolded (U) conformations of apomyoglobin. The molten globule states that were studied in this work include the MG(pH4)(NaCl) state observed at pH 4 and 20 mM NaCl, the MG(pH4)(NaTCA) state observed at pH 4 and 20 mM sodium trichloracetate (NaTCA), the MG(pH2)(NaCl) stat...

1999
A. M. Moulin S. J. O’Shea R. A. Badley P. Doyle M. E. Welland

Microfabricated cantilever sensors were used to measure the surface stress induced by protein adsorption onto a gold surface. Two proteins, immoglobulin G (IgG) and albumin (BSA), were studied. The change of surface stress upon adsorption of IgG was found to be compressive, whereas that of BSA was tensile. This difference is elucidated in terms of protein deformation and packing. Most stress ch...

Journal: :Proceedings of the National Academy of Sciences 2004

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