1. Although alpha-adrenoceptor antagonists have been shown to induce core hypothermia in animals, it is unclear whether the primary mechanism is increased heat loss or decreased heat production. Furthermore, studies have not been performed in humans to determine the role of alpha-adrenoceptors in the maintenance of core temperature. 2. alpha-Adrenoceptor blockade was achieved with three doses o...

BACKGROUND Core body temperature is used to stage and guide the management of hypothermic patients, however obtaining accurate measurements of core temperature is challenging, especially in the pre-hospital context. The Swiss staging model for hypothermia uses clinical indicators to stage hypothermia. The proposed temperature range for clinical stage 1 is <35-32 °C (95-90 °F), for stage 2, <32-...

Biological effects due to RF whole-body exposure can be caused by core temperature rise. According to safety guidelines, therefore, whole-body averaged specific absorption rate (WBA-SAR) is being used as a metric for human protection. The threshold level causing thermal effects was determined based on animal experimental results. In order to investigate the relationship between WBA-SAR and core...

We investigate spin polarized electron transport in ultra-thin Si-Core/Ge-Shell and GeCore/Si-Shell nanowire system using semi-classical Monte Carlo simulation method. Depolarization of electron’s spin occurs in nanowire mainly due to D’yakonov-Perel dephasing (DP-mechanism) and Elliott-Yafet dephasing (EY-mechanism). We studied the dependence of spin dephasing on ultra-thin silicon core diamet...

  Free vibration of sandwich plates with temperature dependent functionally graded (FG) face sheets in various thermal environments is investigated. The material properties of FG face sheets are assumed to be temperature-dependent and vary continuously through the thickness according to a power-law distribution in terms of the volume fractions of the constituents. Also, the material properties ...

in the asemi-gawa area of intermediate high-pressure and low-temperature sanbagawa metamorphic belt in central shikoku, japan, piemontite-quartz schists are common in which cation exchange between piemontite and garnet has been studied. piemontite in contact with garnet usually contains two zones in which core is enriched in mn3+ and surrounded by a rim rich in fe3+. garnet is ca-fe-bearing spe...

aggregation of pharmaceutical proteins reduces the efficiency and increases the cost of production. it can also lead to the reduced efficacy of drug or cause side effects on the patient’s body. investigating how to create them plays an important role to find agents that prevents the aggregation. this study was allocated for understanding the mechanism of formation of the reteplase protein using...

This paper first presents an analysis of the global thermal field in many core processors in deep nanometer (to 16nm) nodes under power and thermal budget. We show that the thermal field can have significant spatiotemporal non-uniformity along with high maximum temperature. We propose spatiotemporal power multiplexing as a proactive method to reduce spatial and temporal temperature gradients. S...