Deformation-based circulating tumor cell (CTC) microchips are a representative diagnostic device for early cancer detection. This type of device usually involves a process of CTC trapping in a confined microgeometry. Further understanding of the CTC flow regime, as well as the threshold passing-through pressure, is a key to the design of deformation-based CTC filtration devices. In the present ...

Virus filtration is a downstream unit operation in the manufacturing of biotherapeutics to remove potential viral contaminations based on size exclusion. While even very small viruses are effectively retained under normal flow conditions, process interruptions can compromise virus-reduction capacity filter. Yet, direct insights into underlying flow-dependent retention and breakthrough mechanism...

In this study, polyvinylidene fluoride (PVDF) ultrafiltration membranes were prepared via immersion precipitation method using a mixture of two solvents triethyl phosphate (TEP) and dimethylacetamide (DMAc), which had different affinities with the nonsolvent (water). Properties of the prepared membranes were characterized using scanning electron microscope (SEM) and contact angle and membrane p...

Simultaneous saccharification, filtration and fermentation (SSFF) was developed for lignocellulosic ethanol production. In SSFF, pretreated lignocellulosic material is enzymatically hydrolyzed in a reactor, while the suspension is continuously pumped through a cross-flow membrane. The retentate goes back to the hydrolysis vessel, while a clear sugar-rich filtrate continuously perfuses through t...

the study of interactions of jet into cross flow at different longitudinal and transverse angles ofjet was studied. the following components were designed and constructed: a low velocity windtunnel to produce the uniform flow, a flat plate with a traverse injection system to simulate the jetinjection, and a spatial rake to measure the total pressure. the tests were carried out atlongitudinal (α...

BACKGROUND The role of kidney hypoxia is considered pivotal in the progression of chronic kidney disease. A widely used method to assess kidney oxygenation is blood oxygen level dependent (BOLD)-magnetic resonance imaging (MRI), but its interpretation remains problematic. The BOLD-MRI signal is the result of kidney oxygen consumption (a proxy of glomerular filtration) and supply (ie, glomerular...

Date juice was treated by cross- flow ultra-filtration with molecular weight cut-off (MWCO) of 5 kDa. Optimized levels of feed brix, TMP and operation time were determined as 47.13, 82.11 psi and 30 min, respectively. Under such conditions, 80.94% decolourisation and 97.78 % turbidity reduction were obtained while loss of glucose and fructose were estimated to be only 3.49% and 9.62%, respectiv...

Date juice was treated by cross- flow ultra-filtration with molecular weight cut-off (MWCO) of 5 kDa. Optimized levels of feed brix, TMP and operation time were determined as 47.13, 82.11 psi and 30 min, respectively. Under such conditions, 80.94% decolourisation and 97.78% turbidity reduction were obtained while loss of glucose and fructose were estimated to be only 3.49% and 9.62%, respective...