Patients with chronic daily headache and overuse of analgesics, triptans, or other acute headache compounds, are considered to suffer from medication-overuse headache (MOH). This implies that medication overuse is the cause of headache chronification. It remains a key question why only two-thirds of patients with chronic migraine-like headache and overuse of pain medication improve after detoxi...

The loading of a Zn-terephthalate based MOF in the inner cavity as well as on the outer walls of a hollow carbon nanofiber (CNF) creates MOF@CNF hybrids. This hybrid ''MOF@CNF'' displayed improved thermal stability as well as gas adsorption compared to the individual counterparts.

Boolean satisfiability (SAT) has become a core technology in many application domains, such as planning and formal verification, and continues to find various new application domains today. The SAT-based approach divides into three steps: encoding, preprocessing, and search. It is often argued that by encoding arbitrary Boolean formulas in conjunctive normal form (CNF), structural properties of...

Introduction: The role of midbrain reticular formation, which includes the nucleus cuneiformis (NCF), as a crucial antinociceptive region in descending pain modulation has long been investigated. In this study, we tried to highlight the role of NCF in morphine-induced antinociception in formalin-induced pain model in rats. Methods: A total of 201 male Wistar rats weighing 260-310 g were used in...

The aim of this study is to prepare and characterize two types of silver-functionalized carbon nanofiber (CNF) composite electrodes, i.e., silver-decorated CNF-epoxy and silver-modified natural zeolite-CNF-epoxy composite electrodes suitable for ibuprofen detection in aqueous solution. Ag carbon nanotube composite electrode exhibited the best electroanalytical parameters through applying precon...

Background The presence of nitric oxide (NO) in the cuneiform nucleus (CnF) has been previously shown. In this study, NG-nitro-L-arginine methyl ester (L-NAME) (an inhibitor of NO synthase), L-arginine (L-Arg) (a precursor of NO), and sodium nitroprusside (SNP) (a donor of NO) were microinjected into the CnF and cardiovascular responses were investigated. Methods Seventy male rats were divide...

Two new species of Bryophaenocladius Thienemann, 1934, Bryophaenocladius mucronatussp. n. and Bryophaenocladius parictericussp. n. are described and illustrated as males. A key to male imagines of the genus from China is presented.