advanced technologies in molecular biology and modern experimental biophysics heavily rely not only on the knowledge of structure of essential proteins but also on their structural dynamics. the function of these bimolecular systems and the pathways along which the biological phenomena take place can be determined based on the knowledge of the molecular structure and behavior. as such, the simp...

brucellosis is a well-known infection in domestic animals which caused by brucella bacterium. due toserious economic and medical consequences of this disease, various efforts have been made to prevent theinfection through the use of recombinant vaccines based on brucella outer membrane protein (omp)antigens. the objectives of the present study were cloning, sequencing and epitope prediction of ...

Cold stress is a major environmental factor that limits plant growth and productivity. Plants have evolved various strategies to adapt these conditions. To better explain the mechanisms used survive challenges, we retrieved cold-responsive genes of Arabidopsis thaliana from Gene Expression Omnibus (GEO) database. The GEO raw data were normalized by quantile method, then differentially expressed...

‘Knowledge-Based Bioinformatics – From analysis to interpretation’, edited by Gil Alterovitz and Marco Ramoni, is a collection (http://onlinelibrary.wiley .com/book/10.1002/9780470669716) of works by 35 authors arranged in 13 Chapters of 4 sections and 2 parts. This book includes diverse knowledgebased bioinformatics issues that arise from rapidly increasing data generated by progressive biolog...

A simple and fast analysis procedure for supernova spectra is presented. Included in the presentation is an introduction to the Sobolev method of radiative transfer, a description of a simple model of a supernova, a catalogue of line profiles illustrating line formation in the simple supernova model, and an example analysis of the SN 1987A photometry and optical spectra. The SN 1987A analysis i...

What a year for David Masopust. The 36-year-old microbiologist won the NIH Director's New Innovator Award in September, shortly after winning the American Society for Microbiology ICAAC Young Investigator Award and the Beckman Foundation Young Investigator Award. Lymphocytes hadn't even crossed his mind 15 years ago. But after some soul searching and tapir tracking in Costa Rica, Masopust began...